Intraductal papillary mucininous neoplasm of the bile ducts: Multimodality assessment with pathologic correlation

Kentaro Takanami, Takayuki Yamada, Masashi Tsuda, Kei Takase, Kazuyuki Ishida, Yasuhiro Nakamura, Atsushi Kanno, Tooru Shimosegawa, Michiaki Unno, Shoki Takahashi

Research output: Contribution to journalArticlepeer-review

56 Citations (Scopus)


Mucin-producing intraductal papillary neoplasm (adenocarcinoma/adenoma) in the bile duct is becoming recognized as a specific type of neoplasm. Since, it bears a striking similarity to intraductal papillary mucinous neoplasms of the pancreas with regard to its histopathologic features, the term "intraductal papillary mucinous neoplasms of the bile duct" (IPMN-B) is frequently used, although no definite terminology or definition has been decided by World Health Organization. This neoplasm lacks ovarian-like stroma and communicates with the bile ducts, unlike biliary mucinous cystic neoplasm (MCN). On the other hand, malignant IPMN-B is categorized as an intraductal-growth type of intrahepatic cholangiocarcinoma (ICC). In comparison to other types of ICC, such as the mass-forming type and periductal-infiltrating type that have poor resectability and an unfavorable prognosis, malignant IPMN-B can be resected and demonstrates a more favorable prognosis. Meanwhile, unlike biliary MCN that is usually confined in a closed cyst, IPMN-B can spread along the mucosal surface of the bile ducts, and it should be widely resected. Therefore, multimodality assessment is needed to ensure the correct diagnosis of IPMN-B. We herein review the imaging findings of IPMN-B with pathologic correlation.

Original languageEnglish
Pages (from-to)447-456
Number of pages10
JournalAbdominal Imaging
Issue number4
Publication statusPublished - 2011 Aug


  • Bile duct
  • FDG
  • Intraductal papillary mucinous neoplasm
  • PET

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology


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