Intraoperative Placement of an Absorbable Spacer Prior to Radiation Therapy for a Malignant Peripheral Nerve Sheath Tumor

Yuki Endo; Taichi Fukuzawa; Masahiro Irie; Hideyuki Sasaki; Hironori Kudo; Ryo Ando; Ryuji Okubo; Saori Katayama; Masatoshi Hashimoto; Kosuke Sato; Masahito Tachibana; Hidekazu Aoki; Masayuki Araya; Koichi Hirabayashi; Shoji Saito; Hidekazu Masaki; Yozo Nakazawa; Yoji Sasahara; Motoshi Wada

doi:10.1159/000524824

Intraoperative Placement of an Absorbable Spacer Prior to Radiation Therapy for a Malignant Peripheral Nerve Sheath Tumor

Yuki Endo, Taichi Fukuzawa, Masahiro Irie, Hideyuki Sasaki, Hironori Kudo, Ryo Ando, Ryuji Okubo, Saori Katayama, Masatoshi Hashimoto, Kosuke Sato, Masahito Tachibana, Hidekazu Aoki, Masayuki Araya, Koichi Hirabayashi, Shoji Saito, Hidekazu Masaki, Yozo Nakazawa, Yoji Sasahara, Motoshi Wada

Research output: Contribution to journal › Article › peer-review

Abstract

A 7-year-6-month-old female was diagnosed with a pelvic malignant peripheral nerve sheath tumor and lymph node metastases. Tumorectomy was performed after four cycles of chemotherapy. A 33-mm cystic lesion was observed around the left iliac muscle after three cycles of postoperative chemotherapy, and proton beam therapy (PBT) was recommended. She was referred for absorbable spacer (AS) placement. The left ovarian appendage (OA) was resected due to the direct tumor infiltration. The right OA was fixed to the uterosacral ligament. The AS was fixed to the lateral pelvis. The PBT (70.3 Gy relative biological effectiveness) was performed successfully with the AS, and she also had the reproducing possibility due to prevention of severe irradiation damage of the right OA. AS eliminated the surgical removal of spacers and enabled us high-dose PBT for residual tumor without severe irradiation damage including infertility.

Original language	English
Pages (from-to)	541-546
Number of pages	6
Journal	Case Reports in Oncology
Volume	15
Issue number	2
DOIs	https://doi.org/10.1159/000524824
Publication status	Published - 2022 May 20
Externally published	Yes

Keywords

Absorbable spacer
Malignant peripheral nerve sheath tumor
Proton beam therapy
Radiation therapy

ASJC Scopus subject areas

Oncology

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10.1159/000524824

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Endo, Y., Fukuzawa, T., Irie, M., Sasaki, H., Kudo, H., Ando, R., Okubo, R., Katayama, S., Hashimoto, M., Sato, K., Tachibana, M., Aoki, H., Araya, M., Hirabayashi, K., Saito, S., Masaki, H., Nakazawa, Y., Sasahara, Y., & Wada, M. (2022). Intraoperative Placement of an Absorbable Spacer Prior to Radiation Therapy for a Malignant Peripheral Nerve Sheath Tumor. Case Reports in Oncology, 15(2), 541-546. https://doi.org/10.1159/000524824

Endo, Y, Fukuzawa, T , Irie, M , Sasaki, H , Kudo, H, Ando, R, Okubo, R , Katayama, S, Hashimoto, M, Sato, K, Tachibana, M , Aoki, H, Araya, M, Hirabayashi, K, Saito, S, Masaki, H, Nakazawa, Y, Sasahara, Y & Wada, M 2022, 'Intraoperative Placement of an Absorbable Spacer Prior to Radiation Therapy for a Malignant Peripheral Nerve Sheath Tumor', Case Reports in Oncology, vol. 15, no. 2, pp. 541-546. https://doi.org/10.1159/000524824

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abstract = "A 7-year-6-month-old female was diagnosed with a pelvic malignant peripheral nerve sheath tumor and lymph node metastases. Tumorectomy was performed after four cycles of chemotherapy. A 33-mm cystic lesion was observed around the left iliac muscle after three cycles of postoperative chemotherapy, and proton beam therapy (PBT) was recommended. She was referred for absorbable spacer (AS) placement. The left ovarian appendage (OA) was resected due to the direct tumor infiltration. The right OA was fixed to the uterosacral ligament. The AS was fixed to the lateral pelvis. The PBT (70.3 Gy relative biological effectiveness) was performed successfully with the AS, and she also had the reproducing possibility due to prevention of severe irradiation damage of the right OA. AS eliminated the surgical removal of spacers and enabled us high-dose PBT for residual tumor without severe irradiation damage including infertility.",

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author = "Yuki Endo and Taichi Fukuzawa and Masahiro Irie and Hideyuki Sasaki and Hironori Kudo and Ryo Ando and Ryuji Okubo and Saori Katayama and Masatoshi Hashimoto and Kosuke Sato and Masahito Tachibana and Hidekazu Aoki and Masayuki Araya and Koichi Hirabayashi and Shoji Saito and Hidekazu Masaki and Yozo Nakazawa and Yoji Sasahara and Motoshi Wada",

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AU - Endo, Yuki

AU - Fukuzawa, Taichi

AU - Irie, Masahiro

AU - Sasaki, Hideyuki

AU - Kudo, Hironori

AU - Ando, Ryo

AU - Okubo, Ryuji

AU - Katayama, Saori

AU - Hashimoto, Masatoshi

AU - Sato, Kosuke

AU - Tachibana, Masahito

AU - Aoki, Hidekazu

AU - Araya, Masayuki

AU - Hirabayashi, Koichi

AU - Saito, Shoji

AU - Masaki, Hidekazu

AU - Nakazawa, Yozo

AU - Sasahara, Yoji

AU - Wada, Motoshi

PY - 2022/5/20

Y1 - 2022/5/20

N2 - A 7-year-6-month-old female was diagnosed with a pelvic malignant peripheral nerve sheath tumor and lymph node metastases. Tumorectomy was performed after four cycles of chemotherapy. A 33-mm cystic lesion was observed around the left iliac muscle after three cycles of postoperative chemotherapy, and proton beam therapy (PBT) was recommended. She was referred for absorbable spacer (AS) placement. The left ovarian appendage (OA) was resected due to the direct tumor infiltration. The right OA was fixed to the uterosacral ligament. The AS was fixed to the lateral pelvis. The PBT (70.3 Gy relative biological effectiveness) was performed successfully with the AS, and she also had the reproducing possibility due to prevention of severe irradiation damage of the right OA. AS eliminated the surgical removal of spacers and enabled us high-dose PBT for residual tumor without severe irradiation damage including infertility.

AB - A 7-year-6-month-old female was diagnosed with a pelvic malignant peripheral nerve sheath tumor and lymph node metastases. Tumorectomy was performed after four cycles of chemotherapy. A 33-mm cystic lesion was observed around the left iliac muscle after three cycles of postoperative chemotherapy, and proton beam therapy (PBT) was recommended. She was referred for absorbable spacer (AS) placement. The left ovarian appendage (OA) was resected due to the direct tumor infiltration. The right OA was fixed to the uterosacral ligament. The AS was fixed to the lateral pelvis. The PBT (70.3 Gy relative biological effectiveness) was performed successfully with the AS, and she also had the reproducing possibility due to prevention of severe irradiation damage of the right OA. AS eliminated the surgical removal of spacers and enabled us high-dose PBT for residual tumor without severe irradiation damage including infertility.

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KW - Malignant peripheral nerve sheath tumor

KW - Proton beam therapy

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Intraoperative Placement of an Absorbable Spacer Prior to Radiation Therapy for a Malignant Peripheral Nerve Sheath Tumor

Abstract

Keywords

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