Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa

Yasuyuki Fujita; Miho Komatsu; San Eun Lee; Yoshihiro Kushida; Chihiro Nakayama-Nishimura; Wakana Matsumura; Shota Takashima; Satoru Shinkuma; Toshifumi Nomura; Naoya Masutomi; Makoto Kawamura; Mari Dezawa; Hiroshi Shimizu

doi:10.1016/j.jid.2020.05.092

Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa

Yasuyuki Fujita, Miho Komatsu, San Eun Lee, Yoshihiro Kushida, Chihiro Nakayama-Nishimura, Wakana Matsumura, Shota Takashima, Satoru Shinkuma, Toshifumi Nomura, Naoya Masutomi, Makoto Kawamura, Mari Dezawa, Hiroshi Shimizu

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Original language	English
Pages (from-to)	198-202.e6
Journal	Journal of Investigative Dermatology
Volume	141
Issue number	1
DOIs	https://doi.org/10.1016/j.jid.2020.05.092
Publication status	Published - 2021 Jan

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Fujita, Y., Komatsu, M., Lee, S. E., Kushida, Y., Nakayama-Nishimura, C., Matsumura, W., Takashima, S., Shinkuma, S., Nomura, T., Masutomi, N., Kawamura, M., Dezawa, M., & Shimizu, H. (2021). Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa. Journal of Investigative Dermatology, 141(1), 198-202.e6. https://doi.org/10.1016/j.jid.2020.05.092

@article{80d24bf5a49d4ab298c54fd1619d3f17,

title = "Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa",

author = "Yasuyuki Fujita and Miho Komatsu and Lee, {San Eun} and Yoshihiro Kushida and Chihiro Nakayama-Nishimura and Wakana Matsumura and Shota Takashima and Satoru Shinkuma and Toshifumi Nomura and Naoya Masutomi and Makoto Kawamura and Mari Dezawa and Hiroshi Shimizu",

note = "Funding Information: YF, NM, and HS are inventors of a patent on the use of Muse cells in the treatment of EB. YK and MD are parties to a codevelopment and coresearch agreement with Life Science Institute, Inc (LSII, Tokyo, Japan). NM is a former employee of LSII. MKa is an employee of LSII. MD has a patent for Muse cells and the isolation method thereof licensed to LSII. MD and HS received a joint research grant from LSII. HS received a medical adviser fee from LSII. Funding Information: The authors thank I.M. Leigh (Queen Mary University of London, Whitechapel, London, UK) for the gift of antibodies against human type VII collagen (LH7.2) and Chihaya Miura for her technical assistance. Life Science Institute, Inc (Tokyo, Japan) supported this work in part by providing funding and CL2020 products. Conceptualization: YF; Data Curation: YF, MKo, YK, WM, MD; Formal Analysis: YF, MKo, YK, TN, MD; Funding Acquisition: HS; Investigation: YF, MKo, SEL, YK, CNN, WM, ST, SS, MD; Methodology: YF, YK, SS, MD; Project Administration: YF, MD; Resources: YF, WM, ST, SS, TN, NM, MKa; Supervision: MD, HS; Validation: WM, TN, MD, HS; Visualization: YF, MKo, SEL, YK, MD; Writing - Original Draft Preparation: YF; Writing - Review and Editing: YF, MKo, SEL, YK, CNN, WM, ST, SS, TN, NM, MKa, MD, HS",

year = "2021",

month = jan,

doi = "10.1016/j.jid.2020.05.092",

language = "English",

volume = "141",

pages = "198--202.e6",

journal = "Journal of Investigative Dermatology",

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}

Fujita, Y, Komatsu, M, Lee, SE, Kushida, Y, Nakayama-Nishimura, C, Matsumura, W, Takashima, S, Shinkuma, S, Nomura, T, Masutomi, N, Kawamura, M, Dezawa, M & Shimizu, H 2021, 'Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa', Journal of Investigative Dermatology, vol. 141, no. 1, pp. 198-202.e6. https://doi.org/10.1016/j.jid.2020.05.092

TY - JOUR

T1 - Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa

AU - Fujita, Yasuyuki

AU - Komatsu, Miho

AU - Lee, San Eun

AU - Kushida, Yoshihiro

AU - Nakayama-Nishimura, Chihiro

AU - Matsumura, Wakana

AU - Takashima, Shota

AU - Shinkuma, Satoru

AU - Nomura, Toshifumi

AU - Masutomi, Naoya

AU - Kawamura, Makoto

AU - Dezawa, Mari

AU - Shimizu, Hiroshi

N1 - Funding Information: YF, NM, and HS are inventors of a patent on the use of Muse cells in the treatment of EB. YK and MD are parties to a codevelopment and coresearch agreement with Life Science Institute, Inc (LSII, Tokyo, Japan). NM is a former employee of LSII. MKa is an employee of LSII. MD has a patent for Muse cells and the isolation method thereof licensed to LSII. MD and HS received a joint research grant from LSII. HS received a medical adviser fee from LSII. Funding Information: The authors thank I.M. Leigh (Queen Mary University of London, Whitechapel, London, UK) for the gift of antibodies against human type VII collagen (LH7.2) and Chihaya Miura for her technical assistance. Life Science Institute, Inc (Tokyo, Japan) supported this work in part by providing funding and CL2020 products. Conceptualization: YF; Data Curation: YF, MKo, YK, WM, MD; Formal Analysis: YF, MKo, YK, TN, MD; Funding Acquisition: HS; Investigation: YF, MKo, SEL, YK, CNN, WM, ST, SS, MD; Methodology: YF, YK, SS, MD; Project Administration: YF, MD; Resources: YF, WM, ST, SS, TN, NM, MKa; Supervision: MD, HS; Validation: WM, TN, MD, HS; Visualization: YF, MKo, SEL, YK, MD; Writing - Original Draft Preparation: YF; Writing - Review and Editing: YF, MKo, SEL, YK, CNN, WM, ST, SS, TN, NM, MKa, MD, HS

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AN - SCOPUS:85088213919

SN - 0022-202X

VL - 141

SP - 198-202.e6

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

IS - 1

ER -

Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa

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