Investigation of blood compatibility for cytocompatibility type a-C:H films

Yasuharu Ohgoe; Yasuyuki Shiraishi; Hidekazu Miura; Kenji Hirdkuri; Akio Fimakiibo; Tomoyuki Yarrbe; Yasuhiro Fiikiii

doi:10.11239/jsmbe.52.O-204

Investigation of blood compatibility for cytocompatibility type a-C:H films

Yasuharu Ohgoe, Yasuyuki Shiraishi, Hidekazu Miura, Kenji Hirdkuri, Akio Fimakiibo, Tomoyuki Yarrbe, Yasuhiro Fiikiii

IDAC - PreClinical Research Center

Research output: Contribution to journal › Article › peer-review

Abstract

In this study, in order to investigate blood compatibility of cytooompatibility type hydrogenated amorphous carbon (a-C:H) film, the a-C:H film coated segmented polyurethane (SPU) scaffold fiber sheet (a-CJf-Scaffold) was implanted at partial aorta desoendens of a goat for 35 days. The scatfold sheet was fabricated by electronspirming method, and the a-C:H film was deposited on the scaffold sheet by nf plasma chemical vapor deposition (CVD) technique. In in-iiw test, it was observed that the a-C.H film ooating surface was uniformly covered by neointima Additionally, the surface had no thrombus formation as an inflammatory reaction and it was shown that tlie a-C:H film coating had a good blood compatibility. These results suggest thatcytooompatibility type a-C:H film lias emetgedasa potential technique for blood interfacing applications.

Original language	English
Pages (from-to)	O-204-O-205
Journal	Transactions of Japanese Society for Medical and Biological Engineering
Volume	52
DOIs	https://doi.org/10.11239/jsmbe.52.O-204
Publication status	Published - 2014 Aug 17

Keywords

A-C:H film
Blood compatibility
Cell growth

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10.11239/jsmbe.52.O-204

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title = "Investigation of blood compatibility for cytocompatibility type a-C:H films",

abstract = "In this study, in order to investigate blood compatibility of cytooompatibility type hydrogenated amorphous carbon (a-C:H) film, the a-C:H film coated segmented polyurethane (SPU) scaffold fiber sheet (a-CJf-Scaffold) was implanted at partial aorta desoendens of a goat for 35 days. The scatfold sheet was fabricated by electronspirming method, and the a-C:H film was deposited on the scaffold sheet by nf plasma chemical vapor deposition (CVD) technique. In in-iiw test, it was observed that the a-C.H film ooating surface was uniformly covered by neointima Additionally, the surface had no thrombus formation as an inflammatory reaction and it was shown that tlie a-C:H film coating had a good blood compatibility. These results suggest thatcytooompatibility type a-C:H film lias emetgedasa potential technique for blood interfacing applications.",

keywords = "A-C:H film, Blood compatibility, Cell growth",

author = "Yasuharu Ohgoe and Yasuyuki Shiraishi and Hidekazu Miura and Kenji Hirdkuri and Akio Fimakiibo and Tomoyuki Yarrbe and Yasuhiro Fiikiii",

year = "2014",

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doi = "10.11239/jsmbe.52.O-204",

language = "English",

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T1 - Investigation of blood compatibility for cytocompatibility type a-C:H films

AU - Ohgoe, Yasuharu

AU - Shiraishi, Yasuyuki

AU - Miura, Hidekazu

AU - Hirdkuri, Kenji

AU - Fimakiibo, Akio

AU - Yarrbe, Tomoyuki

AU - Fiikiii, Yasuhiro

PY - 2014/8/17

Y1 - 2014/8/17

N2 - In this study, in order to investigate blood compatibility of cytooompatibility type hydrogenated amorphous carbon (a-C:H) film, the a-C:H film coated segmented polyurethane (SPU) scaffold fiber sheet (a-CJf-Scaffold) was implanted at partial aorta desoendens of a goat for 35 days. The scatfold sheet was fabricated by electronspirming method, and the a-C:H film was deposited on the scaffold sheet by nf plasma chemical vapor deposition (CVD) technique. In in-iiw test, it was observed that the a-C.H film ooating surface was uniformly covered by neointima Additionally, the surface had no thrombus formation as an inflammatory reaction and it was shown that tlie a-C:H film coating had a good blood compatibility. These results suggest thatcytooompatibility type a-C:H film lias emetgedasa potential technique for blood interfacing applications.

AB - In this study, in order to investigate blood compatibility of cytooompatibility type hydrogenated amorphous carbon (a-C:H) film, the a-C:H film coated segmented polyurethane (SPU) scaffold fiber sheet (a-CJf-Scaffold) was implanted at partial aorta desoendens of a goat for 35 days. The scatfold sheet was fabricated by electronspirming method, and the a-C:H film was deposited on the scaffold sheet by nf plasma chemical vapor deposition (CVD) technique. In in-iiw test, it was observed that the a-C.H film ooating surface was uniformly covered by neointima Additionally, the surface had no thrombus formation as an inflammatory reaction and it was shown that tlie a-C:H film coating had a good blood compatibility. These results suggest thatcytooompatibility type a-C:H film lias emetgedasa potential technique for blood interfacing applications.

KW - A-C:H film

KW - Blood compatibility

KW - Cell growth

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M3 - Article

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SP - O-204-O-205

JO - Transactions of Japanese Society for Medical and Biological Engineering

JF - Transactions of Japanese Society for Medical and Biological Engineering

ER -

Investigation of blood compatibility for cytocompatibility type a-C:H films

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Keywords

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