Investigation of the noncovalent binding mode of covalent proteasome inhibitors around the transition state by combined use of cyclopropylic strain-based conformational restriction and computational modeling

Shuhei Kawamura, Yuka Unno, Motohiro Tanaka, Takuma Sasaki, Akihito Yamano, Takatsugu Hirokawa, Tomoshi Kameda, Akira Asai, Mitsuhiro Arisawa, Satoshi Shuto

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Fingerprint

Dive into the research topics of 'Investigation of the noncovalent binding mode of covalent proteasome inhibitors around the transition state by combined use of cyclopropylic strain-based conformational restriction and computational modeling'. Together they form a unique fingerprint.

Chemistry

Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science