TY - GEN
T1 - IVUS is still alive - Multi parameter analysis for tissue characterization of coronary atherosclerosis and interpretation from acoustic microscopy observation
AU - Saijo, Yoshifumi
PY - 2011
Y1 - 2011
N2 - Is IVUS still alive in the era of OCT which provides higher resolution imaging? Besides easier usability, IVUS is superior to OCT from the point of view of tissue characterization of coronary atherosclerosis. In the present study, multi parameter analysis such as integrated backscatter (IB), Virtual Histology (VH), strain rate imaging and newly developed method named "attenuation imaging" are compared and discussed the interpretation by acoustic microscopy observations. RF signal was obtained from commercial available IVUS systems by the use of fast digitizer card with the sampling frequency of 400 MHz. IB-IVUS image was generated by integrating 128 points of absolute value of RF signal. Conventional IVUS and IB-IVUS show homogeneous fibrous plaque but the deeper region is represented as fibrofatty plaque by VH-IVUS, softer region in the strain rate imaging and low attenuation in the attenuation imaging. Acoustic microscopy observation showed the fibrofatty region as lower attenuation than that of the fibrous tissue. Multi parameter analysis showed the region of soft plaque more clearly than conventional IVUS. As ultrasound reflects mechanical properties of the tissue, IVUS provides important information which was not provided by OCT.
AB - Is IVUS still alive in the era of OCT which provides higher resolution imaging? Besides easier usability, IVUS is superior to OCT from the point of view of tissue characterization of coronary atherosclerosis. In the present study, multi parameter analysis such as integrated backscatter (IB), Virtual Histology (VH), strain rate imaging and newly developed method named "attenuation imaging" are compared and discussed the interpretation by acoustic microscopy observations. RF signal was obtained from commercial available IVUS systems by the use of fast digitizer card with the sampling frequency of 400 MHz. IB-IVUS image was generated by integrating 128 points of absolute value of RF signal. Conventional IVUS and IB-IVUS show homogeneous fibrous plaque but the deeper region is represented as fibrofatty plaque by VH-IVUS, softer region in the strain rate imaging and low attenuation in the attenuation imaging. Acoustic microscopy observation showed the fibrofatty region as lower attenuation than that of the fibrous tissue. Multi parameter analysis showed the region of soft plaque more clearly than conventional IVUS. As ultrasound reflects mechanical properties of the tissue, IVUS provides important information which was not provided by OCT.
KW - acoustic microscopy
KW - atherosclerosis
KW - attenuation imaging
KW - IVUS
KW - tissue strain
UR - http://www.scopus.com/inward/record.url?scp=84869036572&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84869036572&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2011.0499
DO - 10.1109/ULTSYM.2011.0499
M3 - Conference contribution
AN - SCOPUS:84869036572
SN - 9781457712531
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 2005
EP - 2008
BT - 2011 IEEE International Ultrasonics Symposium, IUS 2011
T2 - 2011 IEEE International Ultrasonics Symposium, IUS 2011
Y2 - 18 October 2011 through 21 October 2011
ER -