Limb regeneration in Xenopus laevis froglet

Makoto Suzuki; Nayuta Yakushiji; Yasuaki Nakada; Akira Satoh; Hiroyuki Ide; Koji Tamura

doi:10.1100/tsw.2006.325

Limb regeneration in Xenopus laevis froglet

Makoto Suzuki, Nayuta Yakushiji, Yasuaki Nakada, Akira Satoh, Hiroyuki Ide, Koji Tamura

LIF - Ecological Developmental Adaptability Life Sciences

Research output: Contribution to journal › Review article › peer-review

61 Citations (Scopus)

Abstract

Limb regeneration in amphibians is a representative process of epimorphosis. This type of organ regeneration, in which a mass of undifferentiated cells referred to as the "blastema" proliferate to restore the lost part of the amputated organ, is distinct from morphallaxis as observed, for instance, in Hydra, in which rearrangement of pre-existing cells and tissues mainly contribute to regeneration. In contrast to complete limb regeneration in urodele amphibians, limb regeneration in Xenopus, an anuran amphibian, is restricted. In this review of some aspects regarding adult limb regeneration in Xenopus laevis, we suggest that limb regeneration in adult Xenopus, which is pattern/tissue deficient, also represents epimorphosis.

Original language	English
Pages (from-to)	26-37
Number of pages	12
Journal	TheScientificWorldJournal
Volume	6
Issue number	SUPPL.1
DOIs	https://doi.org/10.1100/tsw.2006.325
Publication status	Published - 2006 May 12

Keywords

Blastema
Dedifferentiation
Epimorphosis
Limb regeneration
Muscle regeneration
Nerve dependence
Spike
Wound healing
Xenopus

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Environmental Science(all)

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10.1100/tsw.2006.325

Cite this

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AU - Suzuki, Makoto

AU - Yakushiji, Nayuta

AU - Nakada, Yasuaki

AU - Satoh, Akira

AU - Ide, Hiroyuki

AU - Tamura, Koji

PY - 2006/5/12

Y1 - 2006/5/12

N2 - Limb regeneration in amphibians is a representative process of epimorphosis. This type of organ regeneration, in which a mass of undifferentiated cells referred to as the "blastema" proliferate to restore the lost part of the amputated organ, is distinct from morphallaxis as observed, for instance, in Hydra, in which rearrangement of pre-existing cells and tissues mainly contribute to regeneration. In contrast to complete limb regeneration in urodele amphibians, limb regeneration in Xenopus, an anuran amphibian, is restricted. In this review of some aspects regarding adult limb regeneration in Xenopus laevis, we suggest that limb regeneration in adult Xenopus, which is pattern/tissue deficient, also represents epimorphosis.

AB - Limb regeneration in amphibians is a representative process of epimorphosis. This type of organ regeneration, in which a mass of undifferentiated cells referred to as the "blastema" proliferate to restore the lost part of the amputated organ, is distinct from morphallaxis as observed, for instance, in Hydra, in which rearrangement of pre-existing cells and tissues mainly contribute to regeneration. In contrast to complete limb regeneration in urodele amphibians, limb regeneration in Xenopus, an anuran amphibian, is restricted. In this review of some aspects regarding adult limb regeneration in Xenopus laevis, we suggest that limb regeneration in adult Xenopus, which is pattern/tissue deficient, also represents epimorphosis.

KW - Blastema

KW - Dedifferentiation

KW - Epimorphosis

KW - Limb regeneration

KW - Muscle regeneration

KW - Nerve dependence

KW - Spike

KW - Wound healing

KW - Xenopus

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Limb regeneration in Xenopus laevis froglet

Abstract

Keywords

ASJC Scopus subject areas

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