Local Measurement of Instantaneous Change in Myocardial Thickness in Swine Heart During Acute Myocardial Ischemia

Yu Obara, Shohei Mori, Masumi Iwai-Takano, Mototaka Arakawa, Susumu Morosawa, Tomohiko Shindo, Hiroaki Yamamoto, Satoshi Yasuda, Hiroaki Shimokawa, Hiroshi Kanai

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

Ultrasound-based local strain rate (SR) measurement can detect the abnormality of the myocardial contraction owing to ischemia with high sensitivity. In the present paper, the local SR measurement using the velocity estimator based on the multifrequency phase differences was applied to the open-chest heart of swine during acute myocardial ischemia to capture the abnormality of the myocardial contraction. For the normal condition, some myocardial layers became thin during the systole even though the whole thickness of the heart wall increased. Interestingly, for the ischemic condition, the rate of the myocardial layers thinning during the systole decreased. In addition, the magnitude of thickening in the measured local SR distribution during the systole decreased in the ischemic condition. This may be caused by acute myocardial ischemia because the magnitude of thickening corresponds to the contractile force of the myocardium and it decreases in acute myocardial ischemia. The difference between the baseline and the ischemic condition was observed in the measured local SR distribution during the systole, even after only a few seconds from the occlusion of the coronary artery.

Original languageEnglish
Title of host publicationIUS 2022 - IEEE International Ultrasonics Symposium
PublisherIEEE Computer Society
ISBN (Electronic)9781665466578
DOIs
Publication statusPublished - 2022
Event2022 IEEE International Ultrasonics Symposium, IUS 2022 - Venice, Italy
Duration: 2022 Oct 102022 Oct 13

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2022-October
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2022 IEEE International Ultrasonics Symposium, IUS 2022
Country/TerritoryItaly
CityVenice
Period22/10/1022/10/13

Keywords

  • Acute myocardial ischemia
  • local strain rate measurement
  • multifrequency phase differences
  • multilayer strain rate measurement
  • myocardial contraction

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