Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats

Mutsuo Kudo; Sachiko Saito; Yuji Owada; Harumi Suzaki; Hisatake Kondo

doi:10.1016/S0169-328X(99)00311-3

Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats

Mutsuo Kudo, Sachiko Saito, Yuji Owada, Harumi Suzaki, Hisatake Kondo

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The localization of mRNA for SHIP2, SH2 domain containing inositol 5-phosphatase SHIP isozyme, was examined by in situ hybridization histochemistry in the brain of developing and mature rats. SHIP2 mRNA was first detected in the ventricular germinal zone at embryonic stages. As the postnatal development proceeded, the expression signal was evident in cell of the white matters, presumptive oligodendrocytes, and no significant expression was seen in neurons throughout the development. Copyright (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	172-177
Number of pages	6
Journal	Molecular Brain Research
Volume	75
Issue number	1
DOIs	https://doi.org/10.1016/S0169-328X(99)00311-3
Publication status	Published - 2000 Jan 10

Keywords

Brain
In situ hybridization histochemistry
Rat
SHIP

ASJC Scopus subject areas

Molecular Biology
Cellular and Molecular Neuroscience

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10.1016/S0169-328X(99)00311-3

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title = "Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats",

abstract = "The localization of mRNA for SHIP2, SH2 domain containing inositol 5-phosphatase SHIP isozyme, was examined by in situ hybridization histochemistry in the brain of developing and mature rats. SHIP2 mRNA was first detected in the ventricular germinal zone at embryonic stages. As the postnatal development proceeded, the expression signal was evident in cell of the white matters, presumptive oligodendrocytes, and no significant expression was seen in neurons throughout the development. Copyright (C) 2000 Elsevier Science B.V.",

keywords = "Brain, In situ hybridization histochemistry, Rat, SHIP",

author = "Mutsuo Kudo and Sachiko Saito and Yuji Owada and Harumi Suzaki and Hisatake Kondo",

note = "Funding Information: This study was supported by Grants-in-aid for Scientific research Nos. 11470001 and 11694235 to H.K. from the Ministry of Education, Science and Culture of Japan and a grant from the Tanaka Orthopedic Clinic Foundation, Hamamatsu, Japan.",

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doi = "10.1016/S0169-328X(99)00311-3",

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T1 - Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats

AU - Kudo, Mutsuo

AU - Saito, Sachiko

AU - Owada, Yuji

AU - Suzaki, Harumi

AU - Kondo, Hisatake

N1 - Funding Information: This study was supported by Grants-in-aid for Scientific research Nos. 11470001 and 11694235 to H.K. from the Ministry of Education, Science and Culture of Japan and a grant from the Tanaka Orthopedic Clinic Foundation, Hamamatsu, Japan.

PY - 2000/1/10

Y1 - 2000/1/10

N2 - The localization of mRNA for SHIP2, SH2 domain containing inositol 5-phosphatase SHIP isozyme, was examined by in situ hybridization histochemistry in the brain of developing and mature rats. SHIP2 mRNA was first detected in the ventricular germinal zone at embryonic stages. As the postnatal development proceeded, the expression signal was evident in cell of the white matters, presumptive oligodendrocytes, and no significant expression was seen in neurons throughout the development. Copyright (C) 2000 Elsevier Science B.V.

AB - The localization of mRNA for SHIP2, SH2 domain containing inositol 5-phosphatase SHIP isozyme, was examined by in situ hybridization histochemistry in the brain of developing and mature rats. SHIP2 mRNA was first detected in the ventricular germinal zone at embryonic stages. As the postnatal development proceeded, the expression signal was evident in cell of the white matters, presumptive oligodendrocytes, and no significant expression was seen in neurons throughout the development. Copyright (C) 2000 Elsevier Science B.V.

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KW - In situ hybridization histochemistry

KW - Rat

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Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats

Abstract

Keywords

ASJC Scopus subject areas

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