Localized gastric amyloidosis that displayed morphological changes over 10 years of observation

Yasushi Takahashi; Waku Hatta; Tomoyuki Koike; Yohei Ogata; Taku Fujiya; Masahiro Saito; Xiaoyi Jin; Kenichiro Nakagawa; Takeshi Kanno; Kiyotaka Asanuma; Kaname Uno; Naoki Asano; Akira Imatani; Fumiyoshi Fujishima; Nagaaki Katoh; Tsuneaki Yoshinaga; Atsushi Masamune

doi:10.2169/internalmedicine.5031-20

Localized gastric amyloidosis that displayed morphological changes over 10 years of observation

Yasushi Takahashi, Waku Hatta, Tomoyuki Koike, Yohei Ogata, Taku Fujiya, Masahiro Saito, Xiaoyi Jin, Kenichiro Nakagawa, Takeshi Kanno, Kiyotaka Asanuma, Kaname Uno, Naoki Asano, Akira Imatani, Fumiyoshi Fujishima, Nagaaki Katoh, Tsuneaki Yoshinaga, Atsushi Masamune

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We herein report an extremely rare case of localized gastric amyloidosis (LGA) with morphological changes during the follow-up. A 71-year-old woman who had a depressed lesion with central elevation in the gastric lower body was diagnosed with LGA. Esophagogastroduodenoscopy at 10 years after the initial examination showed that the lesion had grown and changed morphologically, exhibiting a submucosal tumorlike appearance. Since the lesion was confined to the submucosa, the patient underwent endoscopic submucosal dissection. The final pathological diagnosis was amyloid light-chain (AL)-type LGA. This case may provide useful information regarding the natural history of AL-type LGA.

Original language	English
Pages (from-to)	539-543
Number of pages	5
Journal	Internal Medicine
Volume	60
Issue number	4
DOIs	https://doi.org/10.2169/internalmedicine.5031-20
Publication status	Published - 2021 Feb 15

Keywords

Localized gastric amyloidosis
Morphological change

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10.2169/internalmedicine.5031-20

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Takahashi, Y., Hatta, W., Koike, T., Ogata, Y., Fujiya, T., Saito, M., Jin, X., Nakagawa, K., Kanno, T., Asanuma, K., Uno, K., Asano, N., Imatani, A., Fujishima, F., Katoh, N., Yoshinaga, T., & Masamune, A. (2021). Localized gastric amyloidosis that displayed morphological changes over 10 years of observation. Internal Medicine, 60(4), 539-543. https://doi.org/10.2169/internalmedicine.5031-20

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title = "Localized gastric amyloidosis that displayed morphological changes over 10 years of observation",

abstract = "We herein report an extremely rare case of localized gastric amyloidosis (LGA) with morphological changes during the follow-up. A 71-year-old woman who had a depressed lesion with central elevation in the gastric lower body was diagnosed with LGA. Esophagogastroduodenoscopy at 10 years after the initial examination showed that the lesion had grown and changed morphologically, exhibiting a submucosal tumorlike appearance. Since the lesion was confined to the submucosa, the patient underwent endoscopic submucosal dissection. The final pathological diagnosis was amyloid light-chain (AL)-type LGA. This case may provide useful information regarding the natural history of AL-type LGA.",

keywords = "Localized gastric amyloidosis, Morphological change",

author = "Yasushi Takahashi and Waku Hatta and Tomoyuki Koike and Yohei Ogata and Taku Fujiya and Masahiro Saito and Xiaoyi Jin and Kenichiro Nakagawa and Takeshi Kanno and Kiyotaka Asanuma and Kaname Uno and Naoki Asano and Akira Imatani and Fumiyoshi Fujishima and Nagaaki Katoh and Tsuneaki Yoshinaga and Atsushi Masamune",

year = "2021",

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doi = "10.2169/internalmedicine.5031-20",

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Takahashi, Y, Hatta, W , Koike, T, Ogata, Y, Fujiya, T, Saito, M, Jin, X, Nakagawa, K, Kanno, T, Asanuma, K, Uno, K , Asano, N , Imatani, A , Fujishima, F, Katoh, N, Yoshinaga, T & Masamune, A 2021, 'Localized gastric amyloidosis that displayed morphological changes over 10 years of observation', Internal Medicine, vol. 60, no. 4, pp. 539-543. https://doi.org/10.2169/internalmedicine.5031-20

TY - JOUR

T1 - Localized gastric amyloidosis that displayed morphological changes over 10 years of observation

AU - Takahashi, Yasushi

AU - Hatta, Waku

AU - Koike, Tomoyuki

AU - Ogata, Yohei

AU - Fujiya, Taku

AU - Saito, Masahiro

AU - Jin, Xiaoyi

AU - Nakagawa, Kenichiro

AU - Kanno, Takeshi

AU - Asanuma, Kiyotaka

AU - Uno, Kaname

AU - Asano, Naoki

AU - Imatani, Akira

AU - Fujishima, Fumiyoshi

AU - Katoh, Nagaaki

AU - Yoshinaga, Tsuneaki

AU - Masamune, Atsushi

PY - 2021/2/15

Y1 - 2021/2/15

N2 - We herein report an extremely rare case of localized gastric amyloidosis (LGA) with morphological changes during the follow-up. A 71-year-old woman who had a depressed lesion with central elevation in the gastric lower body was diagnosed with LGA. Esophagogastroduodenoscopy at 10 years after the initial examination showed that the lesion had grown and changed morphologically, exhibiting a submucosal tumorlike appearance. Since the lesion was confined to the submucosa, the patient underwent endoscopic submucosal dissection. The final pathological diagnosis was amyloid light-chain (AL)-type LGA. This case may provide useful information regarding the natural history of AL-type LGA.

AB - We herein report an extremely rare case of localized gastric amyloidosis (LGA) with morphological changes during the follow-up. A 71-year-old woman who had a depressed lesion with central elevation in the gastric lower body was diagnosed with LGA. Esophagogastroduodenoscopy at 10 years after the initial examination showed that the lesion had grown and changed morphologically, exhibiting a submucosal tumorlike appearance. Since the lesion was confined to the submucosa, the patient underwent endoscopic submucosal dissection. The final pathological diagnosis was amyloid light-chain (AL)-type LGA. This case may provide useful information regarding the natural history of AL-type LGA.

KW - Localized gastric amyloidosis

KW - Morphological change

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VL - 60

SP - 539

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JO - Internal Medicine

JF - Internal Medicine

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ER -

Localized gastric amyloidosis that displayed morphological changes over 10 years of observation

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