TY - JOUR
T1 - Lower risk of death from gastric cancer among participants of gastric cancer screening in Japan
T2 - A population-based cohort study
AU - Miyamoto, Akira
AU - Kuriyama, Shinichi
AU - Nishino, Yoshikazu
AU - Tsubono, Yoshitaka
AU - Nakaya, Naoki
AU - Ohmori, Kaori
AU - Kurashima, Kayoko
AU - Shibuya, Daisuke
AU - Tsuji, Ichiro
PY - 2007/1
Y1 - 2007/1
N2 - Objective.: This study aimed to investigate the association between gastric cancer screening and mortality from gastric cancer. Methods.: In 1990, 47,605 Japanese subjects were recruited and completed a questionnaire about participation in gastric cancer screening and life-style. We followed up their vital status through December 2001. In this cohort, 41,394 subjects without a history of cancer were allocated to the screened group or the unscreened group according to their response to the question about gastric cancer screening. We estimated the relative risk (RR) of death from gastric cancer, death from any cause except gastric cancer, and incidence of gastric cancer with adjustment for potential confounding variables. Results.: The risk of death from gastric cancer among the screened group was significantly lower than that among the unscreened group. The multivariate RR of death from gastric cancer for screened individuals compared with those not screened was 0.54 (95% confidence interval [CI]: 0.38, 0.77). The RR of death from any cause except gastric cancer was 0.83 (95% CI: 0.77, 0.90), and the RR of incidence of gastric cancer was 0.94 (95% CI: 0.79, 1.13). Conclusion.: Our data suggest that gastric cancer screening or factors associated with it may be associated with lower mortality from gastric cancer.
AB - Objective.: This study aimed to investigate the association between gastric cancer screening and mortality from gastric cancer. Methods.: In 1990, 47,605 Japanese subjects were recruited and completed a questionnaire about participation in gastric cancer screening and life-style. We followed up their vital status through December 2001. In this cohort, 41,394 subjects without a history of cancer were allocated to the screened group or the unscreened group according to their response to the question about gastric cancer screening. We estimated the relative risk (RR) of death from gastric cancer, death from any cause except gastric cancer, and incidence of gastric cancer with adjustment for potential confounding variables. Results.: The risk of death from gastric cancer among the screened group was significantly lower than that among the unscreened group. The multivariate RR of death from gastric cancer for screened individuals compared with those not screened was 0.54 (95% confidence interval [CI]: 0.38, 0.77). The RR of death from any cause except gastric cancer was 0.83 (95% CI: 0.77, 0.90), and the RR of incidence of gastric cancer was 0.94 (95% CI: 0.79, 1.13). Conclusion.: Our data suggest that gastric cancer screening or factors associated with it may be associated with lower mortality from gastric cancer.
KW - Cohort study
KW - Gastric cancer
KW - Gastric cancer screening
KW - Japanese
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U2 - 10.1016/j.ypmed.2006.07.016
DO - 10.1016/j.ypmed.2006.07.016
M3 - Article
C2 - 16956654
AN - SCOPUS:33846042221
SN - 0091-7435
VL - 44
SP - 12
EP - 19
JO - Preventive Medicine
JF - Preventive Medicine
IS - 1
ER -
