Lupus enteritis during pregnancy: A case-based review

Asuka Nagakawa, Naoko Arata, Asako Mito, Terumi Kaneshige, Masahiro Kitami, Haruhiko Sago, Atsuko Murashima

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Although the symptoms of systemic lupus erythematosus (SLE) worsen during pregnancy, few previous studies have reported lupus enteritis in pregnant women with SLE. A 29-year-old pregnant Japanese woman presented with acute abdomen. Six years before pain onset, she developed pure red cell aplasia and tested positive for anti-Ro (SS-A) and anti-La (SS-B) antibodies. Anti-DNA antibodies were detected two and a half years later. The patient remained asymptomatic until she developed acute abdomen. A mild increase in anti-DNA antibody levels and a mild decrease in complement levels were observed, and abdominal ultrasound and magnetic resonance imaging revealed the presence of large-volume ascites and edematous thickening of the small intestinal wall. These findings established the diagnosis of lupus enteritis. Her condition improved after treatment with prednisolone 50 mg/day, and she delivered a female infant weighing approximately 1810 g at 37 weeks of gestation. Our study suggests that lupus enteritis should be suspected in female patients with autoimmune disease who develop acute abdomen during pregnancy, and that magnetic resonance imaging is useful in its diagnosis.

Original languageEnglish
Pages (from-to)1089-1092
Number of pages4
JournalModern Rheumatology
Issue number6
Publication statusPublished - 2017 Nov 2


  • Enteritis
  • Lupus erythematosus
  • Pregnancy
  • Pure
  • Red cell aplasia
  • Systemic

ASJC Scopus subject areas

  • Rheumatology


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