@inproceedings{0daa75980c7a4395a00c337aec16a9fe,
title = "MC3T3-E1 cell response to hydroxyapatite and alpha-type alumina adsorbed with bovine serum albumin",
abstract = "MC3T3-E1 cell responses, such as cell adhesion and proliferation, to original and bovine serum albumin (BSA) coated disc (original-disc, BSA-disc) of hydroxyapatite (HA) or alpha-type alumina (α-Al2O3) was studied. There was no significant difference in the cell proliferation between BSA-discs and original-discs even after incubated for 14 days, but the cell number at day 14 tended to be higher (p = 0.054) on the BSA-discs of HA than on the original-discs of HA. Incidentally, the amount of adsorbed protein was higher on BSA-discs than on original-discs only until incubated in culture medium for 3 h. BSA adsorption might influence the MC3T3-E1 cell adhesion to HA, as a result the specific adsorption of albumin on HA is likely to affect the expression of the osteoconductivity of materials.",
keywords = "Albumin, Alumina, Hydroxyapatite, Osteoblast, Osteoconductivity",
author = "Jumpei Hayashi and Masakazu Kawashita and Toshiki Miyazaki and Kudo, {Tada Aki} and Hiroyasu Kanetaka and Masami Hashimoto",
year = "2013",
doi = "10.4028/www.scientific.net/KEM.529-530.365",
language = "English",
isbn = "9783037855171",
series = "Key Engineering Materials",
publisher = "Trans Tech Publications Ltd",
number = "1",
pages = "365--369",
booktitle = "Bioceramics 24",
edition = "1",
note = "24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012 ; Conference date: 21-10-2012 Through 24-10-2012",
}