Recently, there have been many reports of patients with radiation-induced myocardial disorder in the late phase. Radiation-induced microvascular damage to the myocardium occurred as a result of the direct effects of radiation on endothelial cells of capillaries of < 0.2 mm in diameter within the myocardium. Radiation-induced myocardial disorder is related with dose-volume histogram. Thus, multiportal irradiation, intensity-modulated radiotherapy and particle beam irradiation are effective to reduce irradiated dose and volume in heart. Natriuretic peptide, ACE inhibitor and lifestyle guidance might have protective value for radiation-induced myocardial disorder: however, there is no definitive evidence clinically.
|Number of pages||4|
|Journal||Japanese Journal of Clinical Radiology|
|Publication status||Published - 2015|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging