Methylmercury binds to a low molecular weight substance in rabbit and human erythrocytes

Akira Naganuma, Nobumasa Imura

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)


Behavior of methylmercury in animal blood was investigated by gel filtration of stroma-free hemolysates from rat, rabbit, and human erythrocytes, treated with methylmercury. In the rabbit and human erythrocytes, methylmercury was bound to a low molecular weight substance rather than hemoglobin, while almost all of methylmercury in the rat erythrocyte was bound to the hemoglobin fraction. The methylmercury-bound substance of low molecular weight in rabbit erythrocytes showed a similar behavior pattern to that of glutathione (GSH) bound with methylmercury on gel filtration with Sephadex G-15 and thin-layer chromatography.

Original languageEnglish
Pages (from-to)613-616
Number of pages4
JournalToxicology and Applied Pharmacology
Issue number3
Publication statusPublished - 1979 Mar 15

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology


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