Micro/nanoelectrochemical probe and chip devices for evaluation of three-dimensional cultured cells

Research output: Contribution to journalReview articlepeer-review

34 Citations (Scopus)


Herein, we present an overview of recent research progress in the development of micro/nanoelectrochemical probe and chip devices for the evaluation of three-dimensional (3D) cultured cells. First, we discuss probe devices: a general outline, evaluation of O2 consumption, enzyme-modified electrodes, evaluation of endogenous enzyme activity, and the collection of cell components from cell aggregates are discussed. The next section is focused on integrated chip devices: a general outline, electrode array devices, smart electrode array devices, droplet detection of 3D cultured cells, cell manipulation using dielectrophoresis (DEP), and electrodeposited hydrogels used for fabrication of 3D cultured cells on chip devices are discussed. Finally, we provide a summary and discussion of future directions of research in this field.

Original languageEnglish
Pages (from-to)4343-4354
Number of pages12
JournalThe Analyst
Issue number23
Publication statusPublished - 2017 Dec 7


Dive into the research topics of 'Micro/nanoelectrochemical probe and chip devices for evaluation of three-dimensional cultured cells'. Together they form a unique fingerprint.

Cite this