We have cloned the cDNAs encoding tyrosinase-related protein-2 (TRP-2) from a human melanoma cDNA library. Transient expression of the isolated cDNA in HeLa cells established that TRP-2 is DOPAchrome tautomerase. Human TRP-2/DOPAchrome tautomerase is composed of 519 amino acids with a molecular weight of 59 000 and has about 84% identity with the mouse counterpart.
|Number of pages||5|
|Journal||BBA - Gene Structure and Expression|
|Publication status||Published - 1994 Apr 6|
- DOPAchrome tautomerase
ASJC Scopus subject areas
- Structural Biology