Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB

Eugene Futai; Tomoteru Kubo; Hiroyuki Sorimachi; Koichi Suzuki; Tatsuya Maeda

doi:10.1016/S0167-4781(00)00256-6

Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB

Eugene Futai, Tomoteru Kubo, Hiroyuki Sorimachi, Koichi Suzuki, Tatsuya Maeda

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

A mammalian homologue of the Aspergillus atypical calpain PalB, PalBH, was identified and its cDNA sequences were determined in human and mouse. The PalBH mRNA was expressed nearly ubiquitously throughout mammalian tissues. When expressed in COS cells, PalBH was enriched in the nucleus, suggesting its role is distinct from that of conventional calpains.

Original language	English
Pages (from-to)	316-319
Number of pages	4
Journal	Biochimica et Biophysica Acta - Gene Structure and Expression
Volume	1517
Issue number	2
DOIs	https://doi.org/10.1016/S0167-4781(00)00256-6
Publication status	Published - 2001 Jan 26
Externally published	Yes

Keywords

Calpain
PalB
PalBH
Proteolysis

ASJC Scopus subject areas

Structural Biology
Biophysics
Biochemistry
Genetics

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10.1016/S0167-4781(00)00256-6

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abstract = "A mammalian homologue of the Aspergillus atypical calpain PalB, PalBH, was identified and its cDNA sequences were determined in human and mouse. The PalBH mRNA was expressed nearly ubiquitously throughout mammalian tissues. When expressed in COS cells, PalBH was enriched in the nucleus, suggesting its role is distinct from that of conventional calpains.",

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AU - Futai, Eugene

AU - Kubo, Tomoteru

AU - Sorimachi, Hiroyuki

AU - Suzuki, Koichi

AU - Maeda, Tatsuya

PY - 2001/1/26

Y1 - 2001/1/26

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AB - A mammalian homologue of the Aspergillus atypical calpain PalB, PalBH, was identified and its cDNA sequences were determined in human and mouse. The PalBH mRNA was expressed nearly ubiquitously throughout mammalian tissues. When expressed in COS cells, PalBH was enriched in the nucleus, suggesting its role is distinct from that of conventional calpains.

KW - Calpain

KW - PalB

KW - PalBH

KW - Proteolysis

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DO - 10.1016/S0167-4781(00)00256-6

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JO - Biochimica et Biophysica Acta - Gene Structure and Expression

JF - Biochimica et Biophysica Acta - Gene Structure and Expression

IS - 2

ER -

Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB

Abstract

Keywords

ASJC Scopus subject areas

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