Molecular Design of Artificial Saccharide Receptors

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


For the development of new receptor molecules that can precisely recognize sugar molecules, we synthesized a number of diboronic acids. Since one boronic acid can react with two OH groups (one diol tot group) to form a boronate ester, one diboronic acid can immobilize two diol units to form a sugar-containing macrocycle. The selectivity can be tuned by the relative spatial position of the two boronic acids and the complexation event can be read out by circular dichroism, UV-Vis, and fluorescence spectroscopy. The nature presents a variety of saccharide structures to us which are already utilized as a "recognition tag" or a "supramolecular building-blocks" in the life processes. If we gain some efficient interfaces to control chemical and physical properties of saccharides, it will become possible to mimic this chemistry in artifical systems. As a research target to challenge this new concept, we can now raise three examples which are currently studied in our laboratory.

Original languageEnglish
Pages (from-to)831-840
Number of pages10
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Issue number10
Publication statusPublished - 1998


  • Artificial receptor
  • Boronic acid
  • Porphyrin
  • Saccharide
  • Sensing


Dive into the research topics of 'Molecular Design of Artificial Saccharide Receptors'. Together they form a unique fingerprint.

Cite this