Morphological and acoustical changes of endothelium by fluid shear stress

Yoshifumi Saijo, Hidehiko Sasaki, Noriyuki Kataoka, Masaaki Sato, Shin ichi Nitta, Motonao Tanaka

Research output: Contribution to journalConference articlepeer-review

1 Citation (Scopus)


Fluid shear stress was applied on the cultured endothelial cells by a continuous flow pump. After 24 hrs of flow stress, the morphological changes and acoustic properties were determined by a specially developed acoustic microscope system with a frequency range between 100 and 210 MHz. The shape of the cells was elongated along a flow direction, and the sound speed of the cytoplasm showed an increasing trend. Acoustic microscopy should be a useful tool for examining the biomechanics of the cells, because it can provide both the morphological and physical properties of the cells in a short time.

Original languageEnglish
Pages (from-to)1333-1336
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Publication statusPublished - 1998
EventProceedings of the 1998 International Ultrasonics Symposium - Sendai, Miyagi, Jpn
Duration: 1998 Oct 51998 Oct 8


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