MR imaging of medullary carcinoma of the breast

Junya Tominaga, Hikaru Hama, Noriko Kimura, Shoki Takahashi

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Purpose: To examine the magnetic resonance imaging (MRI) findings of medullary carcinoma of the breast and to correlate them with histopathologic features. Materials and methods: Eight patients were retrospectively evaluated with pathologically confirmed medullary carcinoma of the breast. T1-weighted fat-saturated, T2-weighted fast spine echo, and gadolinium-enhanced fat-saturated fast spoiled gradient-echo images were obtained. Interpretation of the MRI findings was based on evaluation of the configuration, internal signal intensity, contrast enhancement, and type of the time-intensity curve. Results: Medullary carcinoma showed a lobular shape and a smooth margin, either homogenous or heterogeneous enhancement and delayed peripheral enhancement in the late phase on contrast-enhanced MRI, and either a plateau or washout type with rapid initial rise on the time-intensity curve of the dynamic study. Conclusion: Although the MRI findings showed a close relationship with histopathologic features of medullary carcinoma, it was difficult to differentiate medullary carcinoma from other histologic types of invasive breast carcinomas.

Original languageEnglish
Pages (from-to)525-529
Number of pages5
JournalEuropean Journal of Radiology
Issue number3
Publication statusPublished - 2009 Jun


  • Delayed peripheral enhancement
  • Medullary carcinoma
  • MRI


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