MRI findings from a case of fulminating adult-onset measles encephalitis

Kazutaka Jin; Shigeru Sato; Ryuji Saito; Ayumu Ohnuma; Hiroshi Nomura; Yasuto Itoyama

doi:10.2169/internalmedicine.45.1682

MRI findings from a case of fulminating adult-onset measles encephalitis

Kazutaka Jin, Shigeru Sato, Ryuji Saito, Ayumu Ohnuma, Hiroshi Nomura, Yasuto Itoyama

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

We report a rare case of fulminating adult-onset measles encephalitis. A 34-year-old man developed a comatous state after measles eruptions and ultimately akinetic mutism. Titers of anti-measles IgM antibodies were elevated in both serum and cerebrospinal fluid. Brain magnetic resonance imaging (MRI) 3 months after onset revealed widespread hyperintense lesions in the periventricular white matter and marginal hyperintense lesions in the brainstem on fluid-attenuated inversion recovery and diffusion-weighted images. The marginal lesions in the brainstem are similar to subpial demyelinating lesions seen in postinfectious encephalomyelitis. This case of encephalitis may be related to an autoimmune-mediated process triggered by measles infection.

Original language	English
Pages (from-to)	783-787
Number of pages	5
Journal	Internal Medicine
Volume	45
Issue number	12
DOIs	https://doi.org/10.2169/internalmedicine.45.1682
Publication status	Published - 2006 Jul 18
Externally published	Yes

Keywords

Adult-onset
Brainstem
Diffusion-weighted imaging
MRI
Measles encephalitis
Subpial demyelination

ASJC Scopus subject areas

Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2169/internalmedicine.45.1682

Cite this

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abstract = "We report a rare case of fulminating adult-onset measles encephalitis. A 34-year-old man developed a comatous state after measles eruptions and ultimately akinetic mutism. Titers of anti-measles IgM antibodies were elevated in both serum and cerebrospinal fluid. Brain magnetic resonance imaging (MRI) 3 months after onset revealed widespread hyperintense lesions in the periventricular white matter and marginal hyperintense lesions in the brainstem on fluid-attenuated inversion recovery and diffusion-weighted images. The marginal lesions in the brainstem are similar to subpial demyelinating lesions seen in postinfectious encephalomyelitis. This case of encephalitis may be related to an autoimmune-mediated process triggered by measles infection.",

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AU - Jin, Kazutaka

AU - Sato, Shigeru

AU - Saito, Ryuji

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AU - Nomura, Hiroshi

AU - Itoyama, Yasuto

PY - 2006/7/18

Y1 - 2006/7/18

N2 - We report a rare case of fulminating adult-onset measles encephalitis. A 34-year-old man developed a comatous state after measles eruptions and ultimately akinetic mutism. Titers of anti-measles IgM antibodies were elevated in both serum and cerebrospinal fluid. Brain magnetic resonance imaging (MRI) 3 months after onset revealed widespread hyperintense lesions in the periventricular white matter and marginal hyperintense lesions in the brainstem on fluid-attenuated inversion recovery and diffusion-weighted images. The marginal lesions in the brainstem are similar to subpial demyelinating lesions seen in postinfectious encephalomyelitis. This case of encephalitis may be related to an autoimmune-mediated process triggered by measles infection.

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MRI findings from a case of fulminating adult-onset measles encephalitis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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