MRI findings from a case of fulminating adult-onset measles encephalitis

Kazutaka Jin, Shigeru Sato, Ryuji Saito, Ayumu Ohnuma, Hiroshi Nomura, Yasuto Itoyama

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


We report a rare case of fulminating adult-onset measles encephalitis. A 34-year-old man developed a comatous state after measles eruptions and ultimately akinetic mutism. Titers of anti-measles IgM antibodies were elevated in both serum and cerebrospinal fluid. Brain magnetic resonance imaging (MRI) 3 months after onset revealed widespread hyperintense lesions in the periventricular white matter and marginal hyperintense lesions in the brainstem on fluid-attenuated inversion recovery and diffusion-weighted images. The marginal lesions in the brainstem are similar to subpial demyelinating lesions seen in postinfectious encephalomyelitis. This case of encephalitis may be related to an autoimmune-mediated process triggered by measles infection.

Original languageEnglish
Pages (from-to)783-787
Number of pages5
JournalInternal Medicine
Issue number12
Publication statusPublished - 2006 Jul 18
Externally publishedYes


  • Adult-onset
  • Brainstem
  • Diffusion-weighted imaging
  • MRI
  • Measles encephalitis
  • Subpial demyelination

ASJC Scopus subject areas

  • Internal Medicine


Dive into the research topics of 'MRI findings from a case of fulminating adult-onset measles encephalitis'. Together they form a unique fingerprint.

Cite this