@inproceedings{2e2ca18664344f27b4d14f57597ab5b9,
title = "Multi-capillary based optical sensors for highly sensitive protein detection",
abstract = "A fluorescence measuring method based on glass multi-capillary for detecting trace amounts of proteins is proposed. It promises enhancement of sensitivity due to effects of the adsorption area expansion and the longitudinal excitation. The sensitivity behavior of this method was investigated by using biotin-streptavidin binding. According to experimental examinations, it was found that the sensitivity was improved by a factor of 70 from common glass wells. We also confirmed our measuring system could detect 1 pg/mL of streptavidin. These results suggest that multi-capillary has a potential as a high-sensitive biosensor.",
keywords = "Biosensor, Fluorescence, Immunoassay, Multi-Capillary, Protein",
author = "Yasuhira Okuyama and Takashi Katagiri and Yuji Matsuura",
year = "2017",
month = jan,
day = "1",
doi = "10.1117/12.2275021",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Yasuhiro Awatsuji and Osamu Matoba and Yoshihisa Aizu and Toyohiko Yatagai",
booktitle = "Biomedical Imaging and Sensing Conference",
note = "3rd Biomedical Imaging and Sensing Conference ; Conference date: 19-04-2017 Through 21-04-2017",
}