TY - GEN
T1 - Multi-fluorescence sensor pillars for simultaneous calcium and ph and temperature sensing in chip
AU - Liu, Hengjun
AU - Maruyama, Hisataka
AU - Masuda, Taisuke
AU - Suzuki, Osamu
AU - Arai, Fumihito
N1 - Publisher Copyright:
© 15CBMS-0001.
PY - 2015
Y1 - 2015
N2 - In this paper, we propose the fabrication of multi fluorescence sensor pillars with different sizes in microfluidic chip for simultaneous sensing of calcium, pH and temperature changes. Polyethylene (glycol)-diacrylate (PEG-DA) mixed with different fluorescent dye (fluo-3, FITC, Lumidot 480) was injected into the channel of chip respectively and exposed to UV to fabricate different sensor pillars (calcium sensor, pH sensor and temperature sensor). The fluorescence responses of the sensor pillars to calcium, pH and temperature have been detected using a laser confocal microscopy. The calibration results show that the different sensor pillars can respond to calcium, pH and temperature simultaneously.
AB - In this paper, we propose the fabrication of multi fluorescence sensor pillars with different sizes in microfluidic chip for simultaneous sensing of calcium, pH and temperature changes. Polyethylene (glycol)-diacrylate (PEG-DA) mixed with different fluorescent dye (fluo-3, FITC, Lumidot 480) was injected into the channel of chip respectively and exposed to UV to fabricate different sensor pillars (calcium sensor, pH sensor and temperature sensor). The fluorescence responses of the sensor pillars to calcium, pH and temperature have been detected using a laser confocal microscopy. The calibration results show that the different sensor pillars can respond to calcium, pH and temperature simultaneously.
KW - Fluorescence
KW - Multi sensor
KW - PEG-DA
UR - http://www.scopus.com/inward/record.url?scp=84983233951&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84983233951&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84983233951
T3 - MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 1792
EP - 1794
BT - MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Y2 - 25 October 2015 through 29 October 2015
ER -