Multi-scale computational biomechanics of human circulatory system

Takami Yamaguchi

Research output: Contribution to journalArticlepeer-review


A living system, either as a whole or as a subsystem, such as human circulatory system, is always under the integrated nervous and humoral control of the whole body, i.e., in homeostasis. Multiple feedback mechanisms with mutual interactions among systems, organs, and even tissues provide integrated control of the entire body, These control mechanisms have different spatial coverages, from the micro- to macroscale, and different time constants, from nanoseconds to decades. This paper presents our approach using multi-scale computational analysis to understand macroscale as well as microscale blood flows in human circulatory system.

Original languageEnglish
Pages (from-to)916-921
Number of pages6
JournalNihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B
Issue number4
Publication statusPublished - 2007 Apr


  • Blood flow
  • Computational fluid dynamics
  • Human circulatory system
  • Multi-scale analysis

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Mechanical Engineering


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