Muscle-powered nano mechanical system assembled by optical tweezers

Takayuki Hoshino, Hiroshi Kuroda, Tomohiro Konno, Kazuhiko Ishihara, Reo Kometani, Keisuke Morishima

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


This paper describes assembly of three dimensional cellular structure by optical tweezers. We attempted to construct a three dimensional quasi living machine in small space with muscle cells. Cardiomyocytes were manipulated by using laser optical tweezers at wavelength of 1064 nm. The cellular bridge structure was successful constructed on between PDMS micro pillars. The viability and contraction of that was was confirmed. We also demonstrated a nano assembly of a celldriven nano-mechanical tweezers by using a optical tweezers. The nano mechanical tweezers was designed as single cardiomyocyte contraction force for a nano actuator. A myocyte contraction force is tiny force such as <10 μN, however it is enough large power to drive the nano mechanics. This nano mechanics was three-dimensional carbon structure which was designed for nano tweezers. Focused ion beam induced chemical vapor deposition of the carbon nano mechanics. Optical tweezers allowed to combine the nano tweezers and a single beating cardiomyocyte on it. We demonstrated assembly of single cardiomyocyte powered nano tweezers, which had beams of 150 nm diameter and 20 μm length, and live cardiomyocyte.

Original languageEnglish
Title of host publication2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009
Number of pages4
Publication statusPublished - 2009
Event2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009 - Genoa, Italy
Duration: 2009 Jul 262009 Jul 30

Publication series

Name2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009


Conference2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009


  • Cardiomyocyte
  • Muscl cell
  • Optical tweezres
  • Three dimensional structure


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