TY - JOUR
T1 - Neuro-myelomatosis of the brachial plexus – An unusual site of disease visualized by fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT)
T2 - A case report
AU - Fukunaga, Hisanori
AU - Mutoh, Tatsushi
AU - Tatewaki, Yasuko
AU - Shimomura, Hideo
AU - Totsune, Tomoko
AU - Terao, Chiaki
AU - Miyazawa, Hidemitsu
AU - Taki, Yasuyuki
N1 - Publisher Copyright:
© Am J Case Rep, 2017.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Objective: Rare disease Background: Peripheral or cranial nerve root dysfunction secondary to invasion of the CNS in multiple myeloma is a rare clinical event that is frequently mistaken for other diagnoses. We describe the clinical utility of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET)/CT scanning for diagnosing neuro-myelomatosis. Case Report: A 63-year-old woman whose chief complaints were right shoulder and upper extremity pain underwent MRI and 18F-FDG PET/CT scan. MRI revealed a non-specific brachial plexus tumor. 18F-FDG PET/CT demonstrated intense FDG uptake in multiple intramedullary lesions and in the adjacent right brachial plexus, indicating extramedullary neural involvement associated with multiple myeloma, which was confirmed later by a bone marrow biopsy. Conclusions: This is the first reported case of neuro-myelomatosis of the brachial plexus. It highlights the utility of the 18F-FDG PET/CT scan as a valuable diagnostic modality.
AB - Objective: Rare disease Background: Peripheral or cranial nerve root dysfunction secondary to invasion of the CNS in multiple myeloma is a rare clinical event that is frequently mistaken for other diagnoses. We describe the clinical utility of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET)/CT scanning for diagnosing neuro-myelomatosis. Case Report: A 63-year-old woman whose chief complaints were right shoulder and upper extremity pain underwent MRI and 18F-FDG PET/CT scan. MRI revealed a non-specific brachial plexus tumor. 18F-FDG PET/CT demonstrated intense FDG uptake in multiple intramedullary lesions and in the adjacent right brachial plexus, indicating extramedullary neural involvement associated with multiple myeloma, which was confirmed later by a bone marrow biopsy. Conclusions: This is the first reported case of neuro-myelomatosis of the brachial plexus. It highlights the utility of the 18F-FDG PET/CT scan as a valuable diagnostic modality.
KW - Brachial plexus neuropathies
KW - Central nervous system
KW - Fluorodeoxyglucose F18
KW - Multiple myeloma
KW - Neoplasm invasiveness
KW - Positron-emission tomography
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U2 - 10.12659/AJCR.903761
DO - 10.12659/AJCR.903761
M3 - Article
C2 - 28458390
AN - SCOPUS:85019628879
SN - 1941-5923
VL - 18
SP - 478
EP - 481
JO - American Journal of Case Reports
JF - American Journal of Case Reports
ER -