Neuroanatomical database of normal Japanese brains

Kazunori Sato; Yasuyuki Taki; Hiroshi Fukuda; Ryuta Kawashima

doi:10.1016/j.neunet.2003.06.004

Neuroanatomical database of normal Japanese brains

Kazunori Sato, Yasuyuki Taki, Hiroshi Fukuda, Ryuta Kawashima

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

To develop a high-resolution in vivo human neuroanatomy database for Japanese brains, a data set on 1547 normal subjects between the ages of 16 and 79 years has been collected. First, we determined individual reference brains of normal Japanese for each age and gender group. We found there exists cross-generational changes in brain shape, that is, the young generation has a shorter and wider brain than the older generation. Second, we determined the effect of aging on the volume of gray matter and white matter by voxel based morphometry. A significant negative correlation between the gray matter volume and age was observed. We assume that this kind of database is quite useful to investigators who are engaged in basic neuroscience, clinical diagnostics and evaluation of neuropsychiatric disorders in patients.

Original language	English
Pages (from-to)	1301-1310
Number of pages	10
Journal	Neural Networks
Volume	16
Issue number	9
DOIs	https://doi.org/10.1016/j.neunet.2003.06.004
Publication status	Published - 2003 Nov

Keywords

Age related changes
Brain
Database
Gray matter
Human
Magnetic resonance imaging
Reference brain
White matter

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10.1016/j.neunet.2003.06.004

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title = "Neuroanatomical database of normal Japanese brains",

abstract = "To develop a high-resolution in vivo human neuroanatomy database for Japanese brains, a data set on 1547 normal subjects between the ages of 16 and 79 years has been collected. First, we determined individual reference brains of normal Japanese for each age and gender group. We found there exists cross-generational changes in brain shape, that is, the young generation has a shorter and wider brain than the older generation. Second, we determined the effect of aging on the volume of gray matter and white matter by voxel based morphometry. A significant negative correlation between the gray matter volume and age was observed. We assume that this kind of database is quite useful to investigators who are engaged in basic neuroscience, clinical diagnostics and evaluation of neuropsychiatric disorders in patients.",

keywords = "Age related changes, Brain, Database, Gray matter, Human, Magnetic resonance imaging, Reference brain, White matter",

author = "Kazunori Sato and Yasuyuki Taki and Hiroshi Fukuda and Ryuta Kawashima",

note = "Funding Information: We thank Drs Alan Evans, Alex Zijdenbos, Peter Neelin and Jason Lerch at Montreal Neurological Institute, McGill University, for image data processing, Drs Ryoi Goto, Shuichi Ono, Shigeo Kinomura, Manabu Nakagawa, Motoaki Sugiura, and Jobu Watanabe at IDAC, Tohoku University for data collection and analyses of image data, and Drs Kazuhito Shida and Yoshiyuki Kawazoe at IMR, Tohoku University for development of the database system. This research is supported by grants from the Telecommunications Advancement Organization of Japan, as well as the National Institute of Mental Health, the National Institute of Neurological Disorders and Stroke, the National Institute on Drug Abuse, and the National Cancer Institute of USA.",

year = "2003",

month = nov,

doi = "10.1016/j.neunet.2003.06.004",

language = "English",

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journal = "Neural Networks",

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AU - Sato, Kazunori

AU - Taki, Yasuyuki

AU - Fukuda, Hiroshi

AU - Kawashima, Ryuta

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PY - 2003/11

Y1 - 2003/11

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KW - Database

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KW - Human

KW - Magnetic resonance imaging

KW - Reference brain

KW - White matter

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Neuroanatomical database of normal Japanese brains

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Keywords

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