Neuroprotective Therapy: Failure and Future for Clinical Application

Taizen Nakase

doi:10.1201/b16285-18

Neuroprotective Therapy: Failure and Future for Clinical Application

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Neuroprotective therapy is important not only for protecting neurons in the ischemic penumbra but also for protecting the neurovascular unit in the brain. Numerous potential agents have been studied for neuroprotection under ischemic conditions. However, only one free radical scavenger is currently available for clinical use in Japan. In this chapter, we discuss why many neuroprotective agents have failed to obtain clinical efficacy and what future studies should be focused on for achieving favorable results.

Original language	English
Title of host publication	Rational Basis for Clinical Translation in Stroke Therapy
Publisher	CRC Press
Pages	267-280
Number of pages	14
ISBN (Electronic)	9781466594982
ISBN (Print)	9781466594975
DOIs	https://doi.org/10.1201/b16285-18
Publication status	Published - 2014 Jan 1
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)
Pharmacology, Toxicology and Pharmaceutics(all)
Neuroscience(all)
Chemistry(all)

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10.1201/b16285-18

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Neuroprotective Therapy: Failure and Future for Clinical Application

Abstract

ASJC Scopus subject areas

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