TY - JOUR
T1 - New bioactive glass-ceramic
T2 - Synthesis and application in PMMA bone cement composites
AU - Samad, Hamizah Abd
AU - Jaafar, Mariatti
AU - Othman, Radzali
AU - Kawashita, Masakazu
AU - Razak, Noor Hayati Abdul
PY - 2011
Y1 - 2011
N2 - In present study, a new composition of glass-ceramic was synthesized based on the Na2O-CaO-SiO2-P2O5 glass system. Heat treatment of glass powder was carried out in 2 stages: 600°C as the nucleation temperature and different temperature on crystallization at 850, 950 and 1000°C. The glass-ceramic heat-treated at 950°C was selected as bioactive filler in commercial PMMA bone cement; (PALACOS® LV) due to its ability to form 2 high crystallization phases in comparison with 850 and 1000°C. The results of this newly glass-ceramic filled PMMA bone cement at 0-16 wt% of filler loading were compared with those of hydroxyapatite (HA). The effect of different filler loading on the setting properties was evaluated. The peak temperature during the polymerization of bone cement decreased when the liquid to powder (L/P) ratio was reduced. The setting time, however, did not show any trend when filler loading was increased. In contrast, dough time was observed to decrease with increased filler loading. Apatite morphology was observed on the surface of the glass-ceramic and selected cement after bioactivity test.
AB - In present study, a new composition of glass-ceramic was synthesized based on the Na2O-CaO-SiO2-P2O5 glass system. Heat treatment of glass powder was carried out in 2 stages: 600°C as the nucleation temperature and different temperature on crystallization at 850, 950 and 1000°C. The glass-ceramic heat-treated at 950°C was selected as bioactive filler in commercial PMMA bone cement; (PALACOS® LV) due to its ability to form 2 high crystallization phases in comparison with 850 and 1000°C. The results of this newly glass-ceramic filled PMMA bone cement at 0-16 wt% of filler loading were compared with those of hydroxyapatite (HA). The effect of different filler loading on the setting properties was evaluated. The peak temperature during the polymerization of bone cement decreased when the liquid to powder (L/P) ratio was reduced. The setting time, however, did not show any trend when filler loading was increased. In contrast, dough time was observed to decrease with increased filler loading. Apatite morphology was observed on the surface of the glass-ceramic and selected cement after bioactivity test.
KW - Bioactive bone cement
KW - bioactivity
KW - glass-ceramics
KW - hydroxyapatite
KW - polymethylmethacrylate
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U2 - 10.3233/BME-2011-0673
DO - 10.3233/BME-2011-0673
M3 - Article
C2 - 22182792
AN - SCOPUS:84855173023
SN - 0959-2989
VL - 21
SP - 247
EP - 258
JO - Bio-Medical Materials and Engineering
JF - Bio-Medical Materials and Engineering
IS - 4
ER -