Non-invasive blood glucose measurement using quantum cascade lasers

Y. Matsuura, T. Koyama

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)


A non-invasive blood glucose measurement method using quantum cascade lasers (QCLs) oscillated in mid-infrared region is introduced. A mid-infrared spectroscopy system equipped with a combination of QCLs as light sources and hollow-optical fibers as beam delivery media is developed. As a wavelength of QCL, the wavenumber of 1152 cm-1 that exhibited strong correlation with blood glucose in the optical absorption of human lips is firstly chosen. Then 1186 cm-1 where glucose shows no absorption is also chosen as a reference to remove effects of the baseline variation. By using the QCL-based system, it is shown that the differential absorption between these wavelengths exhibits high correlation with blood glucose level.

Original languageEnglish
Title of host publicationQuantum Sensing and Nano Electronics and Photonics XVI
EditorsManijeh Razeghi, Jay S. Lewis, Eric Tournie, Giti A. Khodaparast
ISBN (Electronic)9781510624948
Publication statusPublished - 2019
EventQuantum Sensing and Nano Electronics and Photonics XVI 2019 - San Francisco, United States
Duration: 2019 Feb 32019 Feb 7

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


ConferenceQuantum Sensing and Nano Electronics and Photonics XVI 2019
Country/TerritoryUnited States
CitySan Francisco


  • ATR spectroscopy
  • Blood glucose
  • Hollow optical fiber
  • Quantum cascade laser


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