Normal Variants in Magnetoencephalography

Stefan Rampp, Yosuke Kakisaka, Sumiya Shibata, Xingtong Wu, Karl Rössler, Michael Buchfelder, Richard C. Burgess

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


Summary:Normal variants, although not occurring frequently, may appear similar to epileptic activity. Misinterpretation may lead to false diagnoses. In the context of presurgical evaluation, normal variants may lead to mislocalizations with severe impact on the viability and success of surgical therapy. While the different variants are well known in EEG, little has been published in regard to their appearance in magnetoencephalography. Furthermore, there are some magnetoencephalography normal variants that have no counterparts in EEG. This article reviews benign epileptiform variants and provides examples in EEG and magnetoencephalography. In addition, the potential of oscillatory configurations in different frequency bands to appear as epileptic activity is discussed.

Original languageEnglish
Pages (from-to)518-536
Number of pages19
JournalJournal of Clinical Neurophysiology
Issue number6
Publication statusPublished - 2020 Nov 1


  • Epilepsy
  • Magnetoencephalography
  • Normal variants


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