Numerical analysis and experimental observation of guidewire motion in a blood vessel model

Kazuto Takashima, Shotaro Tsuzuki, Atomu Ooike, Kiyoshi Yoshinaka, Kaihong Yu, Makoto Ohta, Koji Mori

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


We have developed a computer-based system to simulate a guidewire in blood vessels for surgical planning, intra-operative assistance, and to facilitate the design of new guidewires. In this study, we compared simulation results with experimental results for validation of the simulation system. First, we inserted a commercial guidewire into a poly (vinyl alcohol) hydrogel blood vessel model using a two-axis automatic stage and measured the position of the guidewire tip and the contact force between the guidewire and the vessel. The experimental apparatus can be used not only for the validation of numerical analyses, but also as a simulation system. Second, similarly to the experiment, the motion of the guidewire in the blood vessel model was calculated when the proximal part of the guidewire model was pushed and twisted. The model of the guidewire is constructed with viscoelastic springs and segments, and the proximal part of the guidewire model is constrained by the fixed catheter model. Collisions between the guidewire and the vessel are calculated, and the contact forces are determined according to the stiffness of the vessel wall. The same tendency was seen in the trajectories and the contact force of both the experimental and simulated guidewire tips.

Original languageEnglish
Pages (from-to)1672-1683
Number of pages12
JournalMedical Engineering and Physics
Issue number12
Publication statusPublished - 2014


  • Guidewire
  • Intravascular surgery
  • Numerical analysis
  • Phantom
  • Simulation


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