TY - JOUR
T1 - Olanexidine gluconate formulations as environmental disinfectants for enveloped viruses infection control
AU - Imai, K.
AU - Hagi, A.
AU - Yamagawa, S.
AU - Sano, D.
N1 - Funding Information:
This study may lead to the development of products that may be licensed to the company. After assessment by Tohoku University, this study has been found to have no conflicts of interest. The company had no control over the interpretation of the results or the writing and publication of this study. This collaborative work between Tohoku University and Otsuka Pharmaceutical Factory, Inc., was solely funded by Otsuka Pharmaceutical Factory, Inc.
Publisher Copyright:
© 2021 The Author(s)
PY - 2021/6
Y1 - 2021/6
N2 - This study investigated the potential of olanexidine gluconate as environmental disinfectant against enveloped viruses in the suspension test and three non-porous surface tests. In the suspension test, olanexidine gluconate showed immediate virucidal activity. In addition, non-porous surface tests demonstrated that, although the immediate effect of aqueous formulations was weak, the final virucidal efficacy outcompeted that of ethanol for disinfection. Furthermore, the effectiveness of olanexidine gluconate persisted even after drying on environmental surfaces. This study demonstrated the potential usage of olanexidine gluconate formulations as an environmental disinfectant in the infection control of enveloped viruses.
AB - This study investigated the potential of olanexidine gluconate as environmental disinfectant against enveloped viruses in the suspension test and three non-porous surface tests. In the suspension test, olanexidine gluconate showed immediate virucidal activity. In addition, non-porous surface tests demonstrated that, although the immediate effect of aqueous formulations was weak, the final virucidal efficacy outcompeted that of ethanol for disinfection. Furthermore, the effectiveness of olanexidine gluconate persisted even after drying on environmental surfaces. This study demonstrated the potential usage of olanexidine gluconate formulations as an environmental disinfectant in the infection control of enveloped viruses.
KW - Antiseptic
KW - Coronavirus
KW - Environmental disinfectant
KW - Influenza virus
KW - Olanexidine
KW - Respiratory syncytial virus
UR - http://www.scopus.com/inward/record.url?scp=85104330644&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85104330644&partnerID=8YFLogxK
U2 - 10.1016/j.jhin.2021.03.014
DO - 10.1016/j.jhin.2021.03.014
M3 - Article
C2 - 33766544
AN - SCOPUS:85104330644
SN - 0195-6701
VL - 112
SP - 37
EP - 41
JO - Journal of Hospital Infection
JF - Journal of Hospital Infection
ER -
