Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model

Jun Yamamoto, Kentaro Miyake, Qinghong Han, Yuying Tan, Sachiko Inubushi, Norihiko Sugisawa, Takashi Higuchi, Yoshihiko Tashiro, Hiroto Nishino, Yuki Homma, Ryusei Matsuyama, Sant P. Chawla, Michael Bouvet, Shree Ram Singh, Itaru Endo, Robert M. Hoffman

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Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science