TY - JOUR
T1 - Organic electrochromic timer for enzymatic skin patches
AU - Kai, Hiroyuki
AU - Suda, Wataru
AU - Yoshida, Shotaro
AU - Nishizawa, Matsuhiko
N1 - Funding Information:
The experiment that involved the application of a microneedle array to human skin was conducted according to the protocol approved by Tohoku University. This work was partly supported by MIRAI and Center of Innovation Program (COI-Stream) from Japan Science and Technology Agency (JST) and Grand-in-Aid for Scientific Research A ( 25246016 ) from the Ministry of Education, Culture, Sports, Science and Technology, Japan .
Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - A totally organic and disposable electrochromic timer integrated with an enzymatic electrode and powered by biofuel cells is developed. The cathode of the self-powered electrochromic timer consists of a composite electrochromic film of poly(3,4-ethylenedioxythiophene) (PEDOT) and polyurethane (PU), while the anode is made up of a fructose dehydrogenase (FDH) enzymatic electrode. The electrochromic changes over time (up to 100 min) can be displayed in the device, and the speed of color change can be controlled by changing the resistance between the anode and the cathode. Automatic activation of the timer after placement on a skin is achieved by integrating a porous microneedle array. The electrochromic timer would be used along with a skin patch as a time-lapse display of medical and cosmetic treatments.
AB - A totally organic and disposable electrochromic timer integrated with an enzymatic electrode and powered by biofuel cells is developed. The cathode of the self-powered electrochromic timer consists of a composite electrochromic film of poly(3,4-ethylenedioxythiophene) (PEDOT) and polyurethane (PU), while the anode is made up of a fructose dehydrogenase (FDH) enzymatic electrode. The electrochromic changes over time (up to 100 min) can be displayed in the device, and the speed of color change can be controlled by changing the resistance between the anode and the cathode. Automatic activation of the timer after placement on a skin is achieved by integrating a porous microneedle array. The electrochromic timer would be used along with a skin patch as a time-lapse display of medical and cosmetic treatments.
KW - Biofuel cell
KW - Electrochromism
KW - Skin patch
KW - Transdermal drug delivery
KW - Wound healing
UR - http://www.scopus.com/inward/record.url?scp=85049909099&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049909099&partnerID=8YFLogxK
U2 - 10.1016/j.bios.2018.07.013
DO - 10.1016/j.bios.2018.07.013
M3 - Article
C2 - 30029842
AN - SCOPUS:85049909099
SN - 0956-5663
VL - 123
SP - 108
EP - 113
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
ER -