We determined the physical linkage of six mouse Hox3 homeobox sequences, including a new homeobox sequence (Hox3.5), by analysis of overlapping genomic clones. Additionally, we defined the locations of Hox 1.7 and Hox 1.8 in the Hox 1 cluster. Analysis of the expression patterns of Hox 3.6 and Hox 3.5 during embryogenesis revealed that the relationship between relative position in the Hox 3 cluster and expression domain along antero-posterior axis appears similar to that seen for members of the other Hox clusters.
- Gene Cluster
- Restriction fragment length polymorphism (RFLP)