TY - JOUR
T1 - Outcomes of oculomotor nerve palsy caused by internal carotid artery aneurysm
T2 - Comparison between microsurgical clipping and endovascular coiling
AU - Mino, Masaki
AU - Yoshida, Masahiro
AU - Morita, Takahiro
AU - Tominaga, Teiji
N1 - Publisher Copyright:
© 2015, Japan Neurosurgical Society. All rights reserved.
PY - 2015/12/15
Y1 - 2015/12/15
N2 - The purpose of this study was to compare the clinical outcomes of microsurgical clipping and endovascular coiling in patients with oculomotor nerve palsy (ONP) caused by internal carotid artery (ICA) aneurysm. Among 17 patients with ICA aneurysms presented with ONP, 9 (52.9%) underwent microsurgical clipping and 8 (47.1%) underwent endovascular coiling. Outcomes of functional recovery of ONP were investigated and compared between surgical group and endovascular group. Mean intervals between the onset and treatment were significantly longer in microsurgical group (18.2 days) than in endovascular group (3.5 days). In microsurgical group, complete resolution (CR) of ONP was obtained in 7 of 9 patients (77.8%) and partial resolution (PR) was seen in 2 patients (22.2%). In endovascular group, CR was obtained in 5 of 8 patients (62.5%) and PR was seen in 3 patients (37.5%). The optimal treatment of aneurysm-induced ONP remains controversial; however, present study suggests both procedures are beneficial for achieving functional recovery of ONP. The treatment strategy should be decided primarily considering the general risks of the two procedures, and presence of ONP is not a disadvantageous factor for either procedure.
AB - The purpose of this study was to compare the clinical outcomes of microsurgical clipping and endovascular coiling in patients with oculomotor nerve palsy (ONP) caused by internal carotid artery (ICA) aneurysm. Among 17 patients with ICA aneurysms presented with ONP, 9 (52.9%) underwent microsurgical clipping and 8 (47.1%) underwent endovascular coiling. Outcomes of functional recovery of ONP were investigated and compared between surgical group and endovascular group. Mean intervals between the onset and treatment were significantly longer in microsurgical group (18.2 days) than in endovascular group (3.5 days). In microsurgical group, complete resolution (CR) of ONP was obtained in 7 of 9 patients (77.8%) and partial resolution (PR) was seen in 2 patients (22.2%). In endovascular group, CR was obtained in 5 of 8 patients (62.5%) and PR was seen in 3 patients (37.5%). The optimal treatment of aneurysm-induced ONP remains controversial; however, present study suggests both procedures are beneficial for achieving functional recovery of ONP. The treatment strategy should be decided primarily considering the general risks of the two procedures, and presence of ONP is not a disadvantageous factor for either procedure.
KW - Endovascular Coiling
KW - Internal carotid artery aneurysm
KW - Microsurgical clipping
KW - Oculomotor nerve palsy
UR - http://www.scopus.com/inward/record.url?scp=84949802292&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84949802292&partnerID=8YFLogxK
U2 - 10.2176/nmc.oa.2014-0434
DO - 10.2176/nmc.oa.2014-0434
M3 - Article
C2 - 26369721
AN - SCOPUS:84949802292
SN - 0470-8105
VL - 55
SP - 885
EP - 890
JO - Neurologia Medico-Chirurgica
JF - Neurologia Medico-Chirurgica
IS - 12
ER -