A new, efficient palladium-catalyzed bisfunctionalization of ethylidene malononitriles by addition of acetonitrile and allyl groups is developed for the construction of all-carbon quarternary and tertiary centers simultaneously. This methodology is successfully applied to the synthesis of unsymmetric 1,4-disubstituted C 60.
- β-Acetonitrile-α-allyl addition
- All-carbon quarternary center
- Bisfunctionalization of active alkenes
- Unsymmetric 1,4-disubstituted C