Palladium-catalyzed hydroalkoxylation of methylenecyclopropanes

Drexel H. Camacho, Itaru Nakamura, Shinichi Saito, Yoshinori Yamamoto

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)

Abstract

Hydroalkoxylations proceed by a different path than transition metal catalyzed hydrostannations and hydrosilylations. In the reaction of methylenecyclopropanes 1 with alcohols 2 in the presence of Pd°, the distal bond in the cyclopropane ring is cleaved, and allyl ether 3 is formed selectively. R1 = n- C7H15, PhCH2CH2; R2 = H, PhCH2CH2; R3 = PhCH2, CF3CH2, Et3Si, n-C4H9, etc.

Original languageEnglish
Pages (from-to)3365-3367
Number of pages3
JournalAngewandte Chemie - International Edition
Volume38
Issue number22
DOIs
Publication statusPublished - 1999 Nov 15

Keywords

  • Alcohols
  • Allyl ether formation
  • Hydroalkoxylation reaction
  • Methylenecyclopropanes
  • Palladium

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