Pancreatic endocrine tumors: Epidemiology, pathology, pathophysiology, and diagnosis

C. Shibata, Y. Funayama, I. Sasaki

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


Pancreatic endocrine tumors (PETs) occupy only 2-3% of pancreatic neoplasms and can be divided into two classes depending on whether or not the tumor secretes peptides (functioning or nonfunctioning). Patients with a functioning tumor, in particular, require specific examinations including hormonal tests. Nonfunctioning tumors comprise 30-40% of PETs [1, 2] and are believed to be the most common class of PETs. In this chapter, we overview the history, epidemiology and pathology, clinical manifestations, diagnosis, and treatment of functioning [insulinoma, gastrinoma, glucagonoma, vasoactive intestinal peptide (VIP)-oma, and somatostatinoma) and nonfunctioning PETs

Original languageEnglish
Title of host publicationDiseases of the Pancreas
Subtitle of host publicationCurrent Surgical Therapy
PublisherSpringer Berlin Heidelberg
Number of pages7
ISBN (Print)9783540286554
Publication statusPublished - 2008
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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