TY - GEN
T1 - Parameter exploration of staircase-shape extracellular stimulation for targeted stimulation of myelinated axon
AU - Ueno, Ayako
AU - Karashima, Akihiro
AU - Nakao, Mitsuyuki
AU - Katayama, Norihiro
PY - 2011
Y1 - 2011
N2 - Spatio-temporal dynamics of a mathematical model of myelinated axon in response to staircase-shape extracellular electrical stimulation, which was developed for selective nerve stimulation, is investigated by the computer simulation. It is shown that the response is classified into four types: subthreshold response, cathodic excitation, anodal block and anodal break excitation. Based on the simulation results, simple diagrams representing the response characteristics of the axon are constructed as functions of stimulation parameters and distance between the axon and electrode. The diagram would be useful for determining simulation parameters for dynamic targeted stimulation of myelinated axon.
AB - Spatio-temporal dynamics of a mathematical model of myelinated axon in response to staircase-shape extracellular electrical stimulation, which was developed for selective nerve stimulation, is investigated by the computer simulation. It is shown that the response is classified into four types: subthreshold response, cathodic excitation, anodal block and anodal break excitation. Based on the simulation results, simple diagrams representing the response characteristics of the axon are constructed as functions of stimulation parameters and distance between the axon and electrode. The diagram would be useful for determining simulation parameters for dynamic targeted stimulation of myelinated axon.
UR - http://www.scopus.com/inward/record.url?scp=84055217695&partnerID=8YFLogxK
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U2 - 10.1109/IEMBS.2011.6090204
DO - 10.1109/IEMBS.2011.6090204
M3 - Conference contribution
C2 - 22254459
AN - SCOPUS:84055217695
SN - 9781424441211
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 912
EP - 915
BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Y2 - 30 August 2011 through 3 September 2011
ER -