Pattern Formation on Discrete Gel Matrix Based on DNA Computing

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10 Citations (Scopus)


In this paper, we consider the implementation of a cellular automaton by DNA computing. The proposed system is a reaction–diffusion system built on a structured hydrogel matrix that mimics cellular compartments of biological tissues. Since the cellular automaton is materialized by a hydrogel matrix, the system is called gellular automaton which is theoretically capable of pattern formation and computation by chemical reactions. We focus on technical aspects of the implementation of the gellular automata, such as fabrication of the array of cells, the realization of inter-cellular molecular communication, and how to realize state transitions of cells. Along with the evaluation of each technical element, some simple experimental demonstrations of pattern formation are described.

Original languageEnglish
Pages (from-to)97-111
Number of pages15
JournalNew Generation Computing
Issue number1
Publication statusPublished - 2019 Jan 22


  • Chemical implementation of cellular automata
  • DNA computing
  • Gellular automata
  • Molecular computing
  • Reaction–diffusion system


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