Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes via consecutive carbopalladation

Jian Zhao; Naoki Asao; Yoshinori Yamamoto; Tienan Jin

doi:10.1016/j.tetlet.2014.12.023

Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes via consecutive carbopalladation

Jian Zhao, Naoki Asao, Yoshinori Yamamoto, Tienan Jin

SCI - Research and Analytical Center for Giant Molecules

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Abstract A novel Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes for the construction of the multisubstituted dihydrocyclopenta[a]indene derivatives has been reported. The reaction proceeds efficiently through a four consecutive carbopalladations with alkyne and alkene moieties.

Original language	English
Article number	45547
Pages (from-to)	3133-3136
Number of pages	4
Journal	Tetrahedron Letters
Volume	56
Issue number	23
DOIs	https://doi.org/10.1016/j.tetlet.2014.12.023
Publication status	Published - 2015 May 25

Keywords

Cascade cyclization
Consecutive carbopalladation
Dialkylalkyne
o-Alkynylarylbromide
Pd-catalyzed

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10.1016/j.tetlet.2014.12.023

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title = "Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes via consecutive carbopalladation",

abstract = "Abstract A novel Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes for the construction of the multisubstituted dihydrocyclopenta[a]indene derivatives has been reported. The reaction proceeds efficiently through a four consecutive carbopalladations with alkyne and alkene moieties.",

keywords = "Cascade cyclization, Consecutive carbopalladation, Dialkylalkyne, o-Alkynylarylbromide, Pd-catalyzed",

author = "Jian Zhao and Naoki Asao and Yoshinori Yamamoto and Tienan Jin",

note = "Funding Information: This work was supported by a Scientific Research (B) award from the Japan Society for Promotion of Science (JSPS) (No. 25288043 ) and a World Premier International Research Center Initiative (WPI), MEXT , Japan. Publisher Copyright: {\textcopyright} 2014 Elsevier Ltd.",

year = "2015",

month = may,

day = "25",

doi = "10.1016/j.tetlet.2014.12.023",

language = "English",

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journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes via consecutive carbopalladation

AU - Zhao, Jian

AU - Asao, Naoki

AU - Yamamoto, Yoshinori

AU - Jin, Tienan

N1 - Funding Information: This work was supported by a Scientific Research (B) award from the Japan Society for Promotion of Science (JSPS) (No. 25288043 ) and a World Premier International Research Center Initiative (WPI), MEXT , Japan. Publisher Copyright: © 2014 Elsevier Ltd.

PY - 2015/5/25

Y1 - 2015/5/25

N2 - Abstract A novel Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes for the construction of the multisubstituted dihydrocyclopenta[a]indene derivatives has been reported. The reaction proceeds efficiently through a four consecutive carbopalladations with alkyne and alkene moieties.

AB - Abstract A novel Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes for the construction of the multisubstituted dihydrocyclopenta[a]indene derivatives has been reported. The reaction proceeds efficiently through a four consecutive carbopalladations with alkyne and alkene moieties.

KW - Cascade cyclization

KW - Consecutive carbopalladation

KW - Dialkylalkyne

KW - o-Alkynylarylbromide

KW - Pd-catalyzed

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U2 - 10.1016/j.tetlet.2014.12.023

DO - 10.1016/j.tetlet.2014.12.023

M3 - Article

AN - SCOPUS:84939951478

SN - 0040-4039

VL - 56

SP - 3133

EP - 3136

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 23

M1 - 45547

ER -

Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes via consecutive carbopalladation

Abstract

Keywords

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