Perfluoroacylation of alkenes

Valentine G. Nenajdenko, Ilya D. Gridnev, Elizabeth S. Balenkova

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)

Abstract

Reaction of direct electrophilic perfluoroacylation of different structure alkenes with trifluoroacetic anhydride activated by BF3 · SMe2 complex leads to trifluoromethylalkenylketones with different structure of alkenyl group. Possible composition of the reactive species is considered on the basis of IR and NMR data. Dependence of the reaction course on the substrate structure is discussed.

Original languageEnglish
Pages (from-to)11023-11038
Number of pages16
JournalTetrahedron
Volume50
Issue number37
DOIs
Publication statusPublished - 1994
Externally publishedYes

Keywords

  • boron trifluoride dimethyl sulfide complex
  • electrophilic perfluoroacylation
  • perfluorinated group
  • sulfonium salt
  • trifluoroacetic anhydride

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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