TY - JOUR
T1 - Permeation of manganese, cadmium, zinc, and beryllium through calcium channels of an insect muscle membrane
AU - Fukuda, Jun
AU - Kawa, Kazuyoshi
PY - 1977
Y1 - 1977
N2 - Larval muscle fibers of a beetle, Xylotrupes dichotomus, produce calcium spikes that are maintained when the fibers are bathed in saline solutions containing manganese, cadmium, zinc, or beryllium instead of calcium. This indicates that these cations permeate the calcium channels of the muscle fiber. By contrast, cobalt, nickel, and magnesium are nonpermeating and behave as competitive inhibitors of the permeation of the other divalent cations. Some of the permeating cations suppress delayed rectification.
AB - Larval muscle fibers of a beetle, Xylotrupes dichotomus, produce calcium spikes that are maintained when the fibers are bathed in saline solutions containing manganese, cadmium, zinc, or beryllium instead of calcium. This indicates that these cations permeate the calcium channels of the muscle fiber. By contrast, cobalt, nickel, and magnesium are nonpermeating and behave as competitive inhibitors of the permeation of the other divalent cations. Some of the permeating cations suppress delayed rectification.
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U2 - 10.1126/science.847472
DO - 10.1126/science.847472
M3 - Article
C2 - 847472
AN - SCOPUS:0017594262
SN - 0036-8075
VL - 196
SP - 309
EP - 311
JO - Science
JF - Science
IS - 4287
ER -