Phase-contrast x-ray imaging with x-ray interferometer for medical applications

Tohoru Takeda, Akio Yoneyama, Atsushi Momose, Jin Wu, Tsutomu Zeniya, Thet Thet Lwin, Yoshinori Tsuchiya, Donepudi V. Rao, Kazuyuki Hyodo, Keiichi Hirano, Yuji Aiyoshi, Yuji Itai

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)


Phase-contrast x-ray imaging with x-ray interferometer can depict the minute difference within the biological object, and its sensitivity is about 1000 times higher than that of absorption-contrast method. For biomedical use of this technique, a large monolithic x-ray interferometer and 2 crystal interferometer having a field of view with 25 mm x 25 mm is being developed. Phase-contrast x-ray CT could reveal detail structures within tumor and surrounded tissue, and the vessel imaging of rat liver is also possible using physiological saline at 17.7 keV x-ray energy. Recently, human breast tissues were imaged at 35 keV and the contrast of image was much better than usual absorption contrast x-ray image obtained at 17.7 keV energy.

Original languageEnglish
Pages (from-to)30-37
Number of pages8
JournalIgaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics
Issue number1
Publication statusPublished - 2002


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