Photochemistry of benzophenone immobilized in a major groove of DNA: Formation of thermally reversible interstrand cross-link

Kazuhiko Nakatani; Takashi Yoshida; Isao Saito

doi:10.1021/ja017611r

Photochemistry of benzophenone immobilized in a major groove of DNA: Formation of thermally reversible interstrand cross-link

Kazuhiko Nakatani, Takashi Yoshida, Isao Saito

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

We here report a highly site and sequence selective formation of an interstrand cross-link of _BPU-containing oligomer duplexes. The cross-link was found spontaneously reverted to original oligomers upon heating, providing a new method for the temporary connection of two DNA strands.

Original language	English
Pages (from-to)	2118-2119
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	124
Issue number	10
DOIs	https://doi.org/10.1021/ja017611r
Publication status	Published - 2002 Mar 13
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja017611r

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title = "Photochemistry of benzophenone immobilized in a major groove of DNA: Formation of thermally reversible interstrand cross-link",

abstract = "We here report a highly site and sequence selective formation of an interstrand cross-link of BPU-containing oligomer duplexes. The cross-link was found spontaneously reverted to original oligomers upon heating, providing a new method for the temporary connection of two DNA strands.",

author = "Kazuhiko Nakatani and Takashi Yoshida and Isao Saito",

year = "2002",

month = mar,

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doi = "10.1021/ja017611r",

language = "English",

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T2 - Formation of thermally reversible interstrand cross-link

AU - Nakatani, Kazuhiko

AU - Yoshida, Takashi

AU - Saito, Isao

PY - 2002/3/13

Y1 - 2002/3/13

N2 - We here report a highly site and sequence selective formation of an interstrand cross-link of BPU-containing oligomer duplexes. The cross-link was found spontaneously reverted to original oligomers upon heating, providing a new method for the temporary connection of two DNA strands.

AB - We here report a highly site and sequence selective formation of an interstrand cross-link of BPU-containing oligomer duplexes. The cross-link was found spontaneously reverted to original oligomers upon heating, providing a new method for the temporary connection of two DNA strands.

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DO - 10.1021/ja017611r

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AN - SCOPUS:0037070568

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EP - 2119

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 10

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Photochemistry of benzophenone immobilized in a major groove of DNA: Formation of thermally reversible interstrand cross-link

Abstract

ASJC Scopus subject areas

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