Pitfalls of assessment of autonomic function by heart rate variability

Junichiro Hayano, Emi Yuda

Research output: Contribution to journalReview articlepeer-review

181 Citations (Scopus)


Although analysis of heart rate variability is widely used for the assessment of autonomic function, its fundamental framework linking low-frequency and high-frequency components of heart rate variability with sympathetic and parasympathetic autonomic divisions has developed in the 1980s. This simplified framework is no longer able to deal with much evidence about heart rate variability accumulated over the past half-century. This review addresses the pitfalls caused by the old framework and discusses the points that need attention in autonomic assessment by heart rate variability.

Original languageEnglish
Article number3
JournalJournal of Physiological Anthropology
Issue number1
Publication statusPublished - 2019 Mar 13


  • Autonomic nervous system
  • Cardiorespiratory coupling
  • Heart rate variability
  • Respiratory sinus arrhythmia
  • Spectral analysis


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