Polymeric ethyl glyoxylate in an asymmetric aldol reaction catalyzed by diarylprolinol

Tatsuya Urushima; Yusuke Yasui; Hayato Ishikawa; Yujiro Hayashi

doi:10.1021/ol1009812

Polymeric ethyl glyoxylate in an asymmetric aldol reaction catalyzed by diarylprolinol

Tatsuya Urushima, Yusuke Yasui, Hayato Ishikawa, Yujiro Hayashi

SCI - Chemistry

Tokyo University of Science

Research output: Contribution to journal › Article › peer-review

75 Citations (Scopus)

Abstract

Diarylprolinol was found to be an effective organocatalyst of the direct, enantioselective aldol reaction of commercially available polymeric ethyl glyoxylate, affording γ-ethoxycarbonyl-β-hydroxy aldehydes, versatile synthetic intermediates, in good yield with excellent enantioselectivity.

Original language	English
Pages (from-to)	2966-2969
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	13
DOIs	https://doi.org/10.1021/ol1009812
Publication status	Published - 2010 Jul 2

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abstract = "Diarylprolinol was found to be an effective organocatalyst of the direct, enantioselective aldol reaction of commercially available polymeric ethyl glyoxylate, affording γ-ethoxycarbonyl-β-hydroxy aldehydes, versatile synthetic intermediates, in good yield with excellent enantioselectivity.",

author = "Tatsuya Urushima and Yusuke Yasui and Hayato Ishikawa and Yujiro Hayashi",

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AU - Urushima, Tatsuya

AU - Yasui, Yusuke

AU - Ishikawa, Hayato

AU - Hayashi, Yujiro

PY - 2010/7/2

Y1 - 2010/7/2

N2 - Diarylprolinol was found to be an effective organocatalyst of the direct, enantioselective aldol reaction of commercially available polymeric ethyl glyoxylate, affording γ-ethoxycarbonyl-β-hydroxy aldehydes, versatile synthetic intermediates, in good yield with excellent enantioselectivity.

AB - Diarylprolinol was found to be an effective organocatalyst of the direct, enantioselective aldol reaction of commercially available polymeric ethyl glyoxylate, affording γ-ethoxycarbonyl-β-hydroxy aldehydes, versatile synthetic intermediates, in good yield with excellent enantioselectivity.

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JO - Organic Letters

JF - Organic Letters

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ER -

Polymeric ethyl glyoxylate in an asymmetric aldol reaction catalyzed by diarylprolinol

Abstract

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